Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13063990 | 0.80 | APLNR (0.44) | APLNRFFAR2ALDH1A1L3MBTL1HDAC6 | |
| SCHEMBL17273618 | 0.77 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL1849724 | 0.77 | APLNR (0.41) | APLNRFFAR2ALDH1A1L3MBTL1HDAC6 | |
| SCHEMBL22775197 | 0.77 | APLNR (0.41) | APLNRFFAR2ALDH1A1L3MBTL1HDAC6 | |
| SCHEMBL26126120 | 0.77 | CCR1 (0.40) | HDAC6 | |
| SCHEMBL21909143 | 0.77 | APLNR (0.49) | APLNRFFAR2HDAC6 | |
| Bromide SCHEMBL3873854 | 0.76 | APLNR (0.41) | APLNR | |
| SCHEMBL1857413 | 0.75 | APLNR (0.50) | APLNRFFAR2HDAC6 | |
| SCHEMBL2110025 | 0.75 | APLNR (0.50) | APLNRFFAR2HDAC6 | |
| SCHEMBL26621218 | 0.74 | APLNR (0.33) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064269-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF Αβ-RELATED DISEASES | ASTRAZENECA AB (SE) | 2012-05-18 | — | — | WO | disclosed |