Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436320 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4ES1PR3S1PR4S1PR2 | |
| SCHEMBL26126120 | 0.77 | CCR1 (0.40) | KDM4ES1PR3S1PR4S1PR2S1PR1 | |
| SCHEMBL27658270 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4ES1PR3S1PR4S1PR2 | |
| Bromide SCHEMBL5196642 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4ES1PR3S1PR4S1PR2 | |
| SCHEMBL31477344 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4ES1PR3S1PR4S1PR2 | |
| SCHEMBL4538629 | 0.77 | APLNR (0.41) | ALDH1A1L3MBTL1 | |
| SCHEMBL27961725 | 0.77 | ALDH1A1 (0.34) | ALDH1A1KDM4ES1PR3S1PR4S1PR2 | |
| SCHEMBL27660669 | 0.74 | KDM4E (0.35) | ALDH1A1KDM4ES1PR3S1PR4S1PR2 | |
| SCHEMBL17185818 | 0.74 | S1PR3 (0.33) | ALDH1A1KDM4ES1PR3S1PR4S1PR2 | |
| SCHEMBL13316538 | 0.73 | GBA1 (0.40) | ALDH1A1KDM4ES1PR3S1PR4FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416144-B2 | Benzoxazine oxazolidinone compound, preparation method and application thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2016-08-16 | — | — | US | disclosed |
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | OXA1L, XDH, MYD88 | ALDH1A1 818/4885KDM4E 3712/4885S1PR3 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.