⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768082 | 0.76 | — | — | |
| SCHEMBL14026314 | 0.76 | — | — | |
| SCHEMBL2446417 | 0.76 | — | — | |
| SCHEMBL2223174 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28929577 | 0.74 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL19301621 | 0.74 | NAAA (0.52) | — | |
| SCHEMBL845001 | 0.74 | ALDH1A1 (0.52) | — | |
| SCHEMBL19757607 | 0.73 | EPHX1 (0.65) | — | |
| SCHEMBL3184451 | 0.73 | NAAA (0.66) | — | |
| SCHEMBL19745369 | 0.73 | EPHX1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638036-B1 | COMPOUND FOR INCREASING KINASE ACTIVE AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO LTD (CN) | 2017-08-16 | — | — | EP | disclosed |
| US-9409900-B2 | Compound for increasing kinase active and application thereof | FUJIAN HAIXI PHARMACEUTICALS, INC. (CN) | 2016-08-09 | — | — | US | disclosed |
| EP-2638036-A1 | COMPOUND FOR INCREASING KINASE ACTIVE AND APPLICATION THEREOF | Zhejiang Beta Pharma Incorporation (CN) | 2013-09-18 | — | — | EP | disclosed |
| US-20130225587-A1 | COMPOUND FOR INCREASING KINASE ACTIVE AND APPLICATION THEREOF | ZHEJIANG BETA PHARMA INCORPORATION (CN) | 2013-08-29 | — | — | US | disclosed |
| WO-2012062210-A1 | COMPOUND FOR INCREASING KINASE ACTIVE AND APPLICATION THEREOF | ZHEJIANG BETA PHARMA INC. (CN) | 2012-05-18 | — | — | WO | disclosed |