Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.56 |
| ▸ | DRD4 | P21917 | 7/20 | 0.56 |
| ▸ | DRD3 | P35462 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671551 | 0.82 | CHRM4 (0.54) | MEN1KMT2AALDH1A1USP2KDM4E | |
| SCHEMBL3494237 | 0.76 | DRD4 (0.48) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| SCHEMBL12668381 | 0.74 | MEN1 (0.50) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL2794872 | 0.74 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1243976 | 0.74 | CNR2 (0.55) | KDM4E | |
| SCHEMBL3494523 | 0.74 | OPRM1 (0.49) | DRD2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8681974 | 0.73 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2980930 | 0.72 | DRD2 (0.67) | DRD2DRD4 | |
| SCHEMBL7893044 | 0.72 | CYP2D6 (0.58) | MEN1KMT2A | |
| SCHEMBL6705674 | 0.72 | DRD2 (0.59) | DRD2DRD4ALDH1A1KDM4ECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |