Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787559 | 0.84 | POLB (0.61) | L3MBTL1POLBAPEX1TDP1KDM4E | |
| SCHEMBL4538594 | 0.80 | BDKRB1 (0.44) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4960652 | 0.79 | POLB (0.47) | L3MBTL1POLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL7630480 | 0.78 | RECQL (0.57) | L3MBTL1POLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL6052408 | 0.78 | TDP1 (0.50) | L3MBTL1POLBAPEX1TDP1KDM4E | |
| SCHEMBL20917138 | 0.78 | POLB (0.50) | L3MBTL1POLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL15058294 | 0.78 | POLB (0.50) | L3MBTL1POLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL25233228 | 0.77 | RIPK3 (0.45) | L3MBTL1POLBAPEX1TDP1NAPRT | |
| SCHEMBL25778558 | 0.76 | L3MBTL1 (0.51) | L3MBTL1POLBAPEX1TDP1NAPRT | |
| SCHEMBL29797890 | 0.75 | L3MBTL1 (0.41) | L3MBTL1POLBAPEX1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |