Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | GPX4 | P36969 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787559 | 0.84 | POLB (0.61) | POLBTDP1L3MBTL1APEX1TSHR | |
| SCHEMBL7630480 | 0.81 | RECQL (0.57) | POLBTDP1L3MBTL1APEX1TSHR | |
| SCHEMBL6052408 | 0.81 | TDP1 (0.50) | POLBTDP1L3MBTL1APEX1MEN1 | |
| SCHEMBL15058294 | 0.81 | POLB (0.50) | POLBTDP1L3MBTL1APEX1RECQL | |
| SCHEMBL4960652 | 0.79 | POLB (0.47) | POLBTDP1L3MBTL1APEX1TSHR | |
| SCHEMBL29797575 | 0.78 | POLB (0.49) | POLBTDP1L3MBTL1APEX1 | |
| SCHEMBL4543597 | 0.78 | POLB (0.41) | POLBTDP1L3MBTL1APEX1GPX4 | |
| SCHEMBL4540045 | 0.78 | L3MBTL1 (0.50) | POLBTDP1L3MBTL1APEX1RECQL | |
| SCHEMBL7631926 | 0.77 | POLB (0.46) | POLBTDP1L3MBTL1APEX1TSHR | |
| SCHEMBL1494699 | 0.77 | ALDH1A1 (0.55) | POLBTDP1L3MBTL1APEX1GPX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697763-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | Syneurx International (Taiwan) Corp. (TW) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019076329-A9 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI GUOCHUAN EMIL (CN) | 2019-08-15 | — | — | WO | disclosed |
| WO-2019076329-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI GUOCHUAN EMIL (CN) | 2019-04-25 | — | — | WO | disclosed |