Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | AHSA1 | O95433 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052408 | 0.82 | TDP1 (0.50) | POLBAPEX1TDP1L3MBTL1AHSA1 | |
| SCHEMBL29006050 | 0.82 | AHSA1 (0.40) | AHSA1CES2CES1NOTUMCA12 | |
| SCHEMBL4543597 | 0.82 | POLB (0.41) | POLBAPEX1TDP1L3MBTL1AHSA1 | |
| SCHEMBL4787559 | 0.81 | POLB (0.61) | POLBAPEX1TDP1L3MBTL1NOTUM | |
| SCHEMBL26601277 | 0.79 | KDM4E (0.47) | POLBAPEX1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL20917138 | 0.79 | POLB (0.50) | POLBAPEX1TDP1L3MBTL1NPC1 | |
| SCHEMBL15058294 | 0.79 | POLB (0.50) | POLBAPEX1TDP1L3MBTL1NOTUM | |
| SCHEMBL7630480 | 0.79 | RECQL (0.57) | POLBAPEX1TDP1L3MBTL1NOTUM | |
| SCHEMBL4540045 | 0.79 | L3MBTL1 (0.50) | POLBAPEX1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL29797734 | 0.79 | POLB (0.41) | POLBAPEX1TDP1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044364-B8 | METHOD FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR | AVENTIS PHARMA INC (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1044364-B1 | METHOD FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR | AVENTIS PHARM PROD INC (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1044364-A4 | METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR | AVENTIS PHARM PROD INC (US) | 2004-10-06 | — | — | EP | disclosed |
| US-6599753-B1 | Quantifying a solid-phase reaction; obtain chemical intermediate, incubate with fluorine compound, expose to nuclear magnetic resonance, monitor intensity, compare to control | AVENTIS PHARMACEUTICALS INC. | 2003-07-29 | — | — | US | disclosed |
| EP-1044364-A1 | METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR | Aventis Pharmaceuticals Products Inc. (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999031491-A1 | METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-06-24 | — | — | WO | disclosed |