SCHEMBL4540151

SCHEMBL4540151

COCCC(OC)C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.37
LMNA P02545 1/20 0.34
EPHX2 P34913 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
EPHX1 P07099 1/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
MMP2 P08253 2/20 0.31
CA9 Q16790 2/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12468601 0.98 SHBG (0.33) SHBGLMNAEPHX2SMN1; SMN2
SCHEMBL8383484 0.83 SHBG (0.31) SHBGLMNAEPHX2
SCHEMBL4862281 0.83 SHBG (0.39) SHBGLMNAEPHX2SMN1; SMN2NPSR1
SCHEMBL26986792 0.79 SHBG (0.37) SHBGLMNASMN1; SMN2NPSR1EPHX1
SCHEMBL10335823 0.78 SHBG (0.42) SHBGLMNASMN1; SMN2NPSR1EPHX1
SCHEMBL27128484 0.76 SHBG (0.34) SHBGLMNAEPHX2SMN1; SMN2NPSR1
SCHEMBL27368268 0.76 SHBG (0.39) SHBGEPHX2EPHX1
SCHEMBL21938074 0.76 SHBG (0.52) SHBGLMNASMN1; SMN2EPHX1TP53
SCHEMBL26986694 0.75 TP53 (0.48) SHBGLMNAEPHX2SMN1; SMN2NPSR1
SCHEMBL2946178 0.75 SHBG (0.39) SHBGLMNASMN1; SMN2EPHX1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543310-B A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2019-06-28 CN claimed
WO-2024068382-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-04-04 WO disclosed
WO-2024008770-A1 CATALYST SYSTEM FOR POLYMERIZATION OF AN OLEFIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-11 WO disclosed
US-11840508-B2 Catalyst system for olefin polymerization and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-12-12 US disclosed
CN-106488953-B Polyolefin composition 巴塞尔聚烯烃意大利有限公司 2019-07-02 CN disclosed
CN-109694429-A A kind of polypropylene and its preparation method and application 中国石油化工股份有限公司 2019-04-30 CN disclosed
CN-109694427-A A kind of polypropylene and its preparation method and application 中国石油化工股份有限公司 2019-04-30 CN disclosed
CN-109694428-A A kind of polypropylene and its preparation method and application 中国石油化工股份有限公司 2019-04-30 CN disclosed
CN-106488953-A Polyolefin composition 巴塞尔聚烯烃意大利有限公司 2017-03-08 CN disclosed
EP-2627703-A1 AUTOMOTIVE INTERIOR ELEMENT Basell Poliolefine Italia S.r.l. (IT) 2013-08-21 EP disclosed
WO-2012063972-A1 METHOD FOR COATING REACTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-18 WO disclosed
WO-2012049204-A1 AUTOMOTIVE INTERIOR ELEMENT BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-04-19 WO disclosed
EP-0437264-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-07-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840508-B2 Catalyst system for olefin polymerization and use thereof SQSTM1, SAMM50, HPD SHBG 4501/4885LMNA 4686/4885EPHX2 539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.