SCHEMBL4540189

SCHEMBL4540189

C=CCC(Cc1ccccc1)N(C)C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 10/20 0.46
ADRA2B P18089 2/20 0.46
ADRA2C P18825 2/20 0.46
ADRA1A P35348 2/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2A P28223 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KCNH2 Q12809 1/20 0.46
SIGMAR1 Q99720 3/20 0.43
MAOB P27338 3/20 0.41
OPRD1 P41143 8/20 0.41
OPRM1 P35372 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ADRA2A P08913 1/20 0.41
MAOA P21397 1/20 0.41
SNCA P37840 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL28649942 0.95 OPRK1 (0.45) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL28648570 0.79 CYP2C19 (0.41) OPRK1OPRD1OPRM1SMN1; SMN2
SCHEMBL28127848 0.79 OPRK1 (0.50) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL10591593 0.79 OPRK1 (0.50) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL10591588 0.79 OPRK1 (0.50) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL13453338 0.76 OPRK1 (0.52) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL9915838 0.76 OPRK1 (0.52) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL13453034 0.76 OPRK1 (0.52) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL1071466 0.75 TAAR1 (0.48) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL7322626 0.75 TRPA1 (0.53) OPRK1ADRA2BADRA2CADRA1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618760-B2 Suppresses burying of external additive into toner particles and a change in charging performance of a toner with time; stable development performance; toner and magnetic carrier particles coated with an acrylate polymer maintain uniform charges when mixed/ stirred; amorphous silicon photoreceptors KYOCERA MITA CORPORATION (JP) 2009-11-17 US disclosed
US-20070202426-A1 Two-component developer KYOCERA MITA CORPORATION (JP) 2007-08-30 US disclosed
EP-0324529-B1 Resinous microparticles useful in powdery toner for electrophotography NIPPON PAINT CO LTD (JP) 1996-05-15 EP disclosed
CN-1065861-A ANTIMICROBIAL POLYMERIC QUATERNARY AMMONIUM SALTS ROHM & HAAS (US) 1992-11-04 CN disclosed
US-4968576-A POSITIVE CHARGING ABILITY, IMPROVED FLOWABILITY NIPPON PAINT CO., LTD. (JP) 1990-11-06 US disclosed
EP-0324529-A2 Resinous microparticles useful in powdery toner for electrophotography Nippon Paint Co., Ltd. (JP) 1989-07-19 EP disclosed