Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453338 | 1.00 | OPRK1 (0.52) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| SCHEMBL9915838 | 1.00 | OPRK1 (0.52) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL5084997 | 0.98 | OPRK1 (0.50) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| Bromide SCHEMBL5088614 | 0.98 | OPRK1 (0.50) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| Iodide SCHEMBL5091518 | 0.98 | OPRK1 (0.50) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| SCHEMBL13453010 | 0.83 | ADRA2B (0.53) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| SCHEMBL11117786 | 0.83 | OPRK1 (0.48) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| SCHEMBL14668900 | 0.83 | AOC3 (0.47) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| SCHEMBL28215621 | 0.83 | SLC6A2 (0.44) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 | |
| Iodide SCHEMBL5092821 | 0.82 | OPRK1 (0.47) | OPRK1ADRA2BADRA2CADRA1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | VANTIA LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | CHRM1, ARG1, ARG2 | OPRK1 161/4885ADRA2B 24/4885ADRA2C 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.