Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540201 | 0.85 | MAPT (0.51) | MAPTALOX5APFEN1TSHRRECQL | |
| SCHEMBL7885351 | 0.83 | ALDH1A1 (0.60) | MAPTALOX5APFEN1TSHRRECQL | |
| SCHEMBL3996738 | 0.82 | TSHR (0.73) | TSHRRECQLALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31717616 | 0.74 | PARP1 (0.59) | ALDH1A1TP53HTTSMN1; SMN2 | |
| SCHEMBL22692602 | 0.74 | PKM (0.61) | TSHRALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7121916 | 0.74 | SMN1; SMN2 (0.77) | TSHRALDH1A1TP53HTTGAA | |
| Hydrochloric Acid SCHEMBL31717432 | 0.73 | PARP1 (0.58) | ALDH1A1TP53HTTSMN1; SMN2 | |
| SCHEMBL5349455 | 0.73 | SMN1; SMN2 (0.67) | TSHRALDH1A1TP53HTTGAA | |
| SCHEMBL15917045 | 0.73 | ALOX5AP (0.73) | ALOX5APFEN1ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL17559454 | 0.72 | SMN1; SMN2 (0.65) | TSHRALDH1A1TP53HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009012375-A2 | SQUARATE KINASE INHIBITORS | WYETH (US) | 2009-01-22 | — | — | WO | disclosed |