Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 14/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 13/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537391 | 0.89 | EPHX1 (0.53) | EPHX2EPHX1LMNA | |
| SCHEMBL4537706 | 0.88 | EPHX2 (0.48) | EPHX2EPHX1USP2LMNAKMT2A | |
| SCHEMBL4537187 | 0.88 | EPHX1 (0.52) | EPHX2EPHX1USP2LMNA | |
| SCHEMBL4540068 | 0.86 | EPHX1 (0.54) | EPHX2EPHX1USP2LMNA | |
| SCHEMBL4537521 | 0.86 | LMNA (0.54) | EPHX2EPHX1USP2LMNA | |
| SCHEMBL8061471 | 0.86 | KMT2A (0.43) | EPHX2USP2LMNAKMT2AL3MBTL1 | |
| SCHEMBL4541299 | 0.85 | EPHX1 (0.51) | EPHX2EPHX1LMNA | |
| SCHEMBL4541867 | 0.84 | CNR1 (0.51) | EPHX2EPHX1USP2LMNAKMT2A | |
| SCHEMBL4538146 | 0.84 | CNR1 (0.47) | EPHX2EPHX1USP2LMNAKMT2A | |
| SCHEMBL4539990 | 0.84 | USP2 (0.56) | EPHX2EPHX1USP2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |