Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537706 | 0.95 | EPHX2 (0.48) | CNR1KMT2AMEN1EPHX2LMNA | |
| SCHEMBL8058688 | 0.92 | KMT2A (0.45) | CNR1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL4541867 | 0.90 | CNR1 (0.51) | CNR1KMT2AMEN1EPHX2LMNA | |
| SCHEMBL4539395 | 0.89 | LMNA (0.47) | KMT2AMEN1EPHX2LMNAPOLB | |
| SCHEMBL4537048 | 0.87 | LMNA (0.47) | KMT2AMEN1EPHX2LMNAUSP2 | |
| SCHEMBL4539317 | 0.87 | HSD11B1 (0.49) | KMT2AMEN1LMNAUSP2POLB | |
| SCHEMBL4537427 | 0.87 | SMN1; SMN2 (0.52) | KMT2AEPHX2LMNASMN1; SMN2EPHX1 | |
| SCHEMBL8061471 | 0.86 | KMT2A (0.43) | CNR1KMT2AMEN1EPHX2LMNA | |
| SCHEMBL4536790 | 0.85 | BDKRB1 (0.53) | CNR1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL4539985 | 0.84 | TSHR (0.50) | KMT2AMEN1LMNAL3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |