Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 4/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540579 | 0.78 | FASN (0.59) | CNR1NPC1RAB9AFASNCCR1 | |
| SCHEMBL4535806 | 0.78 | FASN (0.51) | FASNPKMALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4561831 | 0.76 | FASN (0.46) | FASNPKMALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4536291 | 0.71 | MGLL (0.48) | FASNPKMPKLRALDH1A1KDM4E | |
| SCHEMBL4540449 | 0.70 | FASN (0.56) | FASN | |
| SCHEMBL4543314 | 0.69 | FASN (0.57) | FASNPKMALDH1A1MAPTKDM4E | |
| SCHEMBL4562502 | 0.68 | FASN (0.56) | NPC1RAB9AFASNALOX5APFEN1 | |
| SCHEMBL25372763 | 0.67 | CNR1 (0.44) | CNR1NPC1RAB9ACCR1PKM | |
| SCHEMBL4561941 | 0.66 | FASN (0.55) | NPC1RAB9AFASNALOX5APFEN1 | |
| SCHEMBL22235278 | 0.66 | FASN (0.51) | NPC1RAB9AFASNALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637660-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064642-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-05-18 | — | — | WO | disclosed |