SCHEMBL4542263

SCHEMBL4542263

CCCCC(CC)C(C=CC(=O)O)CC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.49
BACE1 P56817 1/20 0.49
CA2 P00918 5/20 0.41
MAPK1 P28482 1/20 0.41
HCAR2 Q8TDS4 3/20 0.37
CA1 P00915 3/20 0.36
GABRP O00591 2/20 0.35
GABRD O14764 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRB1 P18505 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRA3 P34903 2/20 0.35
GABRA2 P47869 2/20 0.35
GABRB2 P47870 2/20 0.35
GABRA4 P48169 2/20 0.35
GABRE P78334 2/20 0.35
GABRA6 Q16445 2/20 0.35
GABRG1 Q8N1C3 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21694697 0.85 ACHE (0.51) ACHEBACE1CA2MAPK1HCAR2
SCHEMBL21694699 0.85 ACHE (0.51) ACHEBACE1CA2MAPK1HCAR2
SCHEMBL10451983 0.82 ACHE (0.49) ACHEBACE1CA2MAPK1HCAR2
SCHEMBL27651696 0.82 ACHE (0.53) ACHEBACE1CA2MAPK1HCAR2
SCHEMBL4826149 0.76 ACHE (0.53) ACHEBACE1CA2MAPK1HCAR2
SCHEMBL4826151 0.76 ACHE (0.53) ACHEBACE1CA2MAPK1HCAR2
SCHEMBL8090945 0.73 ACHE (0.76) ACHEBACE1
SCHEMBL8828842 0.73 ACHE (0.76) ACHEBACE1
SCHEMBL8965243 0.73 ACHE (0.55) ACHEBACE1CA2MAPK1HCAR2
SCHEMBL8965248 0.73 ACHE (0.55) ACHEBACE1CA2MAPK1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060188655-A1 Methods of forming composite coatings PPG INDUSTRIES OHIO, INC. 2006-08-24 US claimed
US-7618677-B2 Method of powder coating weldable substrates PPG INDUSTRIES OHIO, INC. (US) 2009-11-17 US disclosed
US-7592040-B2 Two-tone color effect coating process PPG INDUSTRIES OHIO, INC. (US) 2009-09-22 US disclosed
US-7507440-B2 Methods of forming composite coatings PPG INDUSTRIES OHIO, INC. (US) 2009-03-24 US disclosed
US-20060188655-A1 Methods of forming composite coatings PPG INDUSTRIES OHIO, INC. 2006-08-24 US disclosed
US-20060188652-A1 Two-tone color effect coating process PPG INDUSTRIES OHIO, INC. 2006-08-24 US disclosed
US-20050003082-A1 Method of powder coating weldable substrates PPG INDUSTRIES OHIO, INC. 2005-01-06 US disclosed
EP-0675912-A1 RAPID CURE THERMOSETTING FUNCTIONAL POWDER COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-11 EP disclosed
WO-1994014867-A1 RAPID CURE THERMOSETTING FUNCTIONAL POWDER COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-07-07 WO disclosed
EP-0214448-B1 POWDER COATING COMPOSITIONS OF POLYEPOXIDES AND ACRYLIC COPOLYMERS PPG INDUSTRIES, INC. (US) 1992-01-22 EP disclosed
US-5008335-A Thermosetting; hardness, gloss, chemical resistance PPG INDUSTRIES, INC. (US) 1991-04-16 US disclosed
US-4921913-A Powder coating compositions of polyepoxides and acrylic copolymers PPG INDUSTRIES, INC. (US) 1990-05-01 US disclosed
EP-0322834-A2 Hydroxyalkylamide powder coating curing system PPG INDUSTRIES, INC. (US) 1989-07-05 EP disclosed
US-4801680-A POLYESTERS, EXTERIOR DURABILITY PPG INDUSTRIES, INC. (US) 1989-01-31 US disclosed
EP-0214448-A2 Powder coating compositions of polyepoxides and acrylic copolymers PPG INDUSTRIES, INC. (US) 1987-03-18 EP disclosed