Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965248 | 1.00 | ACHE (0.55) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL30527786 | 0.94 | ACHE (0.49) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL29177079 | 0.92 | ACHE (0.47) | ACHEBACE1HCAR2CA1ACE2 | |
| SCHEMBL3470044 | 0.87 | ACE2 (0.51) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL900317 | 0.87 | GABRP (0.48) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL900319 | 0.87 | GABRP (0.48) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL17021602 | 0.87 | GABRP (0.48) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL8948267 | 0.83 | ACHE (0.42) | ACHEBACE1CA2MAPK1CA1 | |
| SCHEMBL8948270 | 0.83 | ACHE (0.42) | ACHEBACE1CA2MAPK1CA1 | |
| SCHEMBL9579602 | 0.82 | ACHE (0.46) | ACHEBACE1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568546-B1 | BRIDGED CYCLIC KETAL DERIVATIVES | GLAXO GROUP LTD (GB) | 1995-04-12 | — | — | EP | claimed |
| EP-0568546-A1 | BRIDGED CYCLIC KETAL DERIVATIVES. | GLAXO GROUP LTD (GB) | 1993-11-10 | — | — | EP | claimed |
| WO-1992012156-A1 | BRIDGED CYCLIC KETAL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | claimed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| EP-0398373-B1 | Electrophotographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1996-02-21 | — | — | EP | disclosed |
| EP-0399469-B1 | Electrophotographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1996-02-21 | — | — | EP | disclosed |
| US-5178983-A | Binder resin | FUJI PHOTO FILM CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5112713-A | Lithographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| US-5110701-A | Acrylated polyester as macromolecular monomer in graft copolymer | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0399469-A1 | Electrophotographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |
| EP-0398373-A1 | Electrophotographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |