Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543731 | 0.91 | POLB (0.40) | POLBDUSP3PTPN5PTPN11MCL1 | |
| SCHEMBL4233003 | 0.86 | MAPT (0.50) | MAPTHTR7HTR6HTR1AMEN1 | |
| SCHEMBL4225100 | 0.86 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4224408 | 0.84 | POLB (0.48) | POLBDUSP3PTPN5PTPN11MAPT | |
| SCHEMBL4231056 | 0.84 | EGFR (0.46) | HTR6CNR1ALDH1A1MCL1 | |
| SCHEMBL4540052 | 0.80 | GPR17 (0.37) | MAPTHTR6MEN1KMT2AMCL1 | |
| SCHEMBL4223918 | 0.75 | POLB (0.43) | POLBDUSP3PTPN5PTPN11MAPT | |
| SCHEMBL4223972 | 0.74 | GPR17 (0.37) | POLBMAPTHTR6KMT2AALDH1A1 | |
| SCHEMBL4223932 | 0.74 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9215791 | 0.72 | SLC6A4 (0.52) | POLBDUSP3PTPN5PTPN11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006089-A2 | A2 ADENOSINE RECEPTOR AGONISTS | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-01-08 | — | — | WO | disclosed |