Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543731 | 0.87 | POLB (0.40) | GPR17MCL1 | |
| SCHEMBL4231056 | 0.84 | EGFR (0.46) | MCL1HTR6SMN1; SMN2 | |
| SCHEMBL4233057 | 0.84 | GPR17 (0.38) | GPR17MCL1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4542962 | 0.80 | POLB (0.45) | MCL1KMT2AMEN1MAPTHTR6 | |
| SCHEMBL4225100 | 0.80 | MAPT (0.40) | KMT2AMEN1NPSR1CA12CA1 | |
| SCHEMBL4233003 | 0.80 | MAPT (0.50) | KMT2AMEN1LMNAMAPTHTR6 | |
| SCHEMBL4223972 | 0.78 | GPR17 (0.37) | GPR17MCL1KMT2ALMNACA12 | |
| SCHEMBL4219372 | 0.75 | LMNA (0.41) | KMT2AMEN1LMNAPKMNPSR1 | |
| SCHEMBL828951 | 0.73 | EGFR (0.47) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL24598179 | 0.71 | THRB (0.42) | KMT2AMEN1LMNAPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006089-A2 | A2 ADENOSINE RECEPTOR AGONISTS | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-01-08 | — | — | WO | disclosed |