SCHEMBL454335

SCHEMBL454335

CO[Si](OC)(OC)O[Si](O[Si](OC)(OC)OC)(O[Si](OC)(OC)OC)C1CC2C=CC1C2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201969 0.84 ALDH1A1 (0.31) KDM4ELMNA
SCHEMBL6783803 0.84 KDM4E (0.30) KDM4ELMNA
SCHEMBL2605524 0.81
SCHEMBL5701581 0.80
SCHEMBL5701391 0.76 KDM4E (0.33) KDM4E
SCHEMBL5701650 0.76 KDM4E (0.31) KDM4E
SCHEMBL20362136 0.75
SCHEMBL16362628 0.75
SCHEMBL16704814 0.75 KDM4E (0.33) KDM4E
SCHEMBL18947927 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371641-A Cyclic olefin ring-opening polymer and hydride thereof 杭州睿丰融创科技有限公司 2025-01-28 CN disclosed
US-20170253679-A1 HIGHLY SELECTIVE POLYNORBORNENE HOMOPOLYMER MEMBRANES FOR NATURAL GAS UPGRADING ARAMCO SERVICES COMANY 2017-09-07 US disclosed
EP-2634197-B1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO KK (JP) 2017-05-31 EP disclosed
EP-2614091-B1 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO KK (JP) 2016-04-20 EP disclosed
CN-103080150-B Catalyst for polymerization of norbornene monomer and method for preparing norbornene polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 2015-09-02 CN disclosed
US-8835580-B2 Catalyst for norbornene monomer polymerization and method for producing norbornene polymer SHOWA DENKO K.K. (JP) 2014-09-16 US disclosed
US-8598288-B2 Catalyst for polymerization of norbornene monomers, method for producing norbornene polymer, method for producing norbornene copolymer, norbornene polymer and transition metal complex SHOWA DENKO K.K. (JP) 2013-12-03 US disclosed
US-20130261271-A1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2013-10-03 US disclosed
EP-2634197-A1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-09-04 EP disclosed
EP-2614091-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-07-17 EP disclosed
US-20130059993-A1 CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX SHOWA DENKO K.K. (JP) 2013-03-07 US disclosed
WO-2012033227-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059993-A1 CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX NNMT, PPOX, DNMT1 KDM4E 3501/4885LMNA 4080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.