SCHEMBL4543370

SCHEMBL4543370

O=C(c1ccccc1)c1ccc(CN(CCO)CCO)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.63
HDAC1 Q13547 2/20 0.50
HTT P42858 1/20 0.50
ALDH1A1 P00352 3/20 0.48
BCHE P06276 3/20 0.48
GAA P10253 1/20 0.47
SRD5A2 P31213 1/20 0.47
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
HSP90AB1 P08238 1/20 0.46
LMNA P02545 1/20 0.46
HPGD P15428 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14722293 0.88 ACHE (0.55) ACHEHDAC1HTTALDH1A1BCHE
SCHEMBL15356107 0.86 ACHE (0.54) ACHEALDH1A1BCHESRD5A2HDAC8
SCHEMBL20224023 0.86 HTT (0.53) ACHEHDAC1HTTALDH1A1GAA
Benzophenone SCHEMBL9545189 0.85 ALDH1A1 (0.61) ACHEALDH1A1GAASRD5A2LMNA
SCHEMBL25934214 0.85 ACHE (0.56) ACHEHDAC1HTTBCHEGAA
SCHEMBL27233078 0.85 ACHE (0.51) ACHEHDAC1HTTALDH1A1GAA
SCHEMBL5636987 0.84 MEP1B (0.57) ACHEHDAC1HTTALDH1A1SRD5A2
SCHEMBL19221715 0.84 ACHE (0.57) ACHEBCHEHPGD
SCHEMBL18546022 0.81 HTT (0.69) ACHEHDAC1HTTALDH1A1BCHE
SCHEMBL79747 0.81 HTT (0.62) ACHEHDAC1HTTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371308-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2016-06-21 US claimed
EP-2638077-B1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST AS (DK) 2015-01-07 EP claimed
EP-2638078-B1 NEW ROUTES TO POLYACRYLATES COLOPLAST AS (DK) 2015-01-07 EP claimed
EP-2744834-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES Lambson Limited (GB) 2014-06-25 EP claimed
US-20130296454-A1 ROUTES TO POLYACRYLATES COLOPLAST A/S (DK) 2013-11-07 US claimed
US-20130289155-A1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2013-10-31 US claimed
WO-2013026451-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES COLOPLAST A/S (DK) 2013-02-28 WO claimed
US-11998664-B2 Ureteral stent and manufacture method therefor JIANGSU BIOSURF BIOTECH CO., LTD (CN) 2024-06-04 US disclosed
EP-2585497-B1 HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS COLOPLAST AS (DK) 2023-08-09 EP disclosed
US-20220062511-A1 URETER STENT AND MANUFACTURE METHOD THEREFOR JIANGSU BIOSURF BIOTECH CO., LTD. (CN) 2022-03-03 US disclosed
CN-110835397-B Self-crosslinking water-based photocuring polyurethane and preparation method and application thereof 江苏百赛飞生物科技有限公司 2021-12-31 CN disclosed
CN-109954169-B Coating composition, coating method and coated product 江苏百赛飞生物科技有限公司 2021-09-14 CN disclosed
CN-109957083-B Unsaturated polyol, photocurable polyurethane prepared from unsaturated polyol and preparation methods of unsaturated polyol and photocurable polyurethane 江苏百赛飞生物科技有限公司 2021-06-29 CN disclosed
WO-2013026451-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES COLOPLAST A/S (DK) 2013-02-28 WO disclosed
WO-2012062333-A1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2012-05-18 WO disclosed
WO-2012062333-A1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2012-05-18 WO disclosed
WO-2012062334-A1 NEW ROUTES TO POLYACRYLATES COLOPLAST A/S (DK) 2012-05-18 WO disclosed
WO-2012062334-A1 NEW ROUTES TO POLYACRYLATES COLOPLAST A/S (DK) 2012-05-18 WO disclosed
WO-2011160641-A2 HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160641-A2 HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed