Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543507 | 1.00 | HRH3 (0.49) | HRH3HRH2HRH1ACHECXCR4 | |
| SCHEMBL13787355 | 0.94 | HRH3 (0.51) | HRH3HRH2HRH1ACHECXCR4 | |
| Fumaric Acid SCHEMBL4544046 | 0.86 | HRH3 (0.45) | HRH3HRH2HRH1ACHE | |
| Fumaric Acid SCHEMBL4544051 | 0.86 | HRH3 (0.45) | HRH3HRH2HRH1ACHE | |
| SCHEMBL4383218 | 0.81 | HRH3 (0.76) | HRH3HRH2HRH1ACHE | |
| SCHEMBL4387149 | 0.81 | HRH3 (0.76) | HRH3HRH2HRH1ACHE | |
| SCHEMBL4394330 | 0.78 | HRH3 (0.40) | HRH3ACHE | |
| SCHEMBL737100 | 0.78 | HRH3 (0.46) | HRH3CXCR4 | |
| SCHEMBL1377295 | 0.78 | HRH3 (0.46) | HRH3CXCR4 | |
| SCHEMBL737684 | 0.78 | HRH3 (0.46) | HRH3CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | HRH3 452/4885HRH2 391/4885HRH1 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.