Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | ADH1B | P00325 | 1/20 | 0.55 |
| ▸ | ADH1C | P00326 | 1/20 | 0.55 |
| ▸ | ADH1A | P07327 | 1/20 | 0.55 |
| ▸ | ADH4 | P08319 | 1/20 | 0.55 |
| ▸ | ADH7 | P40394 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL27499722 | 1.00 | TSHR (0.61) | TSHRTHRBEPHX1ADH1BADH1C | |
| Decane SCHEMBL28763742 | 0.96 | TSHR (0.58) | TSHRTHRBEPHX1ADH1BADH1C | |
| Pentane SCHEMBL4667362 | 0.88 | TSHR (0.58) | TSHRTHRBEPHX1ADH1BADH1C | |
| Pentane SCHEMBL5367252 | 0.88 | — | — | |
| Acetaldehyde SCHEMBL11420862 | 0.85 | SLC22A1 (0.72) | TSHRALDH1A1DNM1HSD17B10 | |
| Cetyl Alcohol SCHEMBL27479769 | 0.85 | TSHR (0.72) | TSHRTHRBEPHX1ADH1BADH1C | |
| Acetaldehyde SCHEMBL17238759 | 0.85 | SLC22A1 (0.72) | TSHRALDH1A1DNM1HSD17B10 | |
| Tetrahexylammonium SCHEMBL7548222 | 0.85 | SLC22A1 (0.72) | TSHRALDH1A1DNM1HSD17B10 | |
| Acetaldehyde SCHEMBL17238774 | 0.85 | SLC22A1 (0.72) | TSHRALDH1A1DNM1HSD17B10 | |
| Nonane SCHEMBL29223324 | 0.85 | TSHR (0.61) | TSHRTHRBEPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204637-B1 | PROCESS FOR THE PREPARATION OF ISOTRETINOIN | RANBAXY LAB LTD (IN) | 2005-04-20 | — | — | EP | claimed |
| US-20050027143-A1 | Process for the preparation of beta-ionylideneacetaldehyde | RANBAXY LABORATORIES LIMITED (IN) | 2005-02-03 | — | — | US | claimed |
| EP-1421054-A2 | PROCESS FOR THE PREPARATION OF BETA-IONYLIDENEACETALDEHYDE | RANBAXY LABORATORIES, LTD. (IN) | 2004-05-26 | — | — | EP | claimed |
| WO-2003018522-A2 | PROCESS FOR THE PREPARATION OF BETA-IONYLIDENEACETALDEHYDE | RANBAXY LABORATORIES LIMITED (IN) | 2003-03-06 | — | — | WO | claimed |
| JP-2003506349-A | — | — | 2003-02-18 | — | — | JP | claimed |
| US-6441226-B1 | ONE STEP | RANBAXY LABORATORIES LIMITED (IN) | 2002-08-27 | — | — | US | claimed |
| EP-1204637-A1 | PROCESS FOR THE PREPARATION OF ISOTRETINOIN | RANBAXY LABORATORIES, LTD. (IN) | 2002-05-15 | — | — | EP | claimed |
| WO-2001009089-A1 | PROCESS FOR THE PREPARATION OF ISOTRETINOIN | RANBAXY LABORATORIES LIMITED (IN) | 2001-02-08 | — | — | WO | claimed |
| EP-0430808-B1 | Dihydropyran derivatives, their processes of preparation and their use | RHONE POULENC NUTRITION ANIMAL (FR) | 1995-03-29 | — | — | EP | claimed |
| US-5250710-A | Dihydropyran derivatives, processes for preparation and use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1993-10-05 | — | — | US | claimed |
| JP-3209376-A | — | — | None | — | — | JP | disclosed |
| US-11977060-B1 | Methods of detecting predators in algal cultures | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2024-05-07 | — | — | US | disclosed |
| CN-111499662-B | Isotretinoin C15-triphenylphosphine chloride and preparation method and application thereof | 上海新华联制药有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111499662-A | Isotretinoin C15-triphenylphosphine chloride and preparation method and application thereof | 上海新华联制药有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111454141-A | Isotretinoin condensation compound and preparation method and application thereof | 上海新华联制药有限公司 | 2020-07-28 | — | — | CN | disclosed |
| US-5145972-A | PROCESS FOR PREPARING HALO ACETALS FROM ENAMINES | RHONE-POULENC NUTRITION ANIMALE (FR) | 1992-09-08 | — | — | US | disclosed |
| JP-H03209376-A | DIHYDROPYRAN DERIVATIVE, PROCESS FOR PREPARATION AND USE | RHONE POULENC NUTRITION ANIMAL | 1991-09-12 | — | — | JP | disclosed |
| EP-0430807-A1 | Process for the preparation of halogeno-acetals from enamines | RHONE-POULENC NUTRITION ANIMALE (FR) | 1991-06-05 | — | — | EP | disclosed |
| EP-0430808-A1 | Dihydropyran derivatives, their processes of preparation and their use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1991-06-05 | — | — | EP | disclosed |
| US-3974181-A | Trimethyl-1,4-dioxaspiro[4,5]dec-7-en-8-methanol | HOFFMANN-LA ROCHE INC. (US) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050027143-A1 | Process for the preparation of beta-ionylideneacetaldehyde | ALDH1A2, ADH1B, ADH4 | TSHR 260/4885THRB 43/4885EPHX1 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.