Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715014 | 1.00 | CA2 (0.44) | CA2CA1MAPK1MMP1MMP2 | |
| SCHEMBL29968461 | 0.84 | CA2 (0.56) | CA2CA1MAPK1 | |
| SCHEMBL2495651 | 0.84 | CA2 (0.56) | CA2CA1MAPK1 | |
| SCHEMBL29488726 | 0.84 | CA2 (0.56) | CA2CA1MAPK1 | |
| SCHEMBL7898617 | 0.84 | HDAC7 (0.46) | CA2CA1MAPK1LMNATSHR | |
| SCHEMBL2187996 | 0.84 | CA2 (0.56) | CA2CA1MAPK1 | |
| SCHEMBL14535364 | 0.84 | CA2 (0.56) | CA2CA1MAPK1 | |
| SCHEMBL5692168 | 0.84 | CA2 (0.56) | CA2CA1MAPK1 | |
| SCHEMBL8042218 | 0.84 | MMP1 (0.40) | CA2MMP1MMP2MMP3MMP7 | |
| SCHEMBL3686551 | 0.83 | CA2 (0.65) | CA2CA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379310-B1 | VARIABLE STIFFNESS HEATING CATHETER | MICRUS ENDOVASCULAR CORP (US) | 2009-11-18 | — | — | EP | claimed |
| EP-0457692-B1 | Cyanate resin-based foams | HEXCEL CORP (US) | 1995-09-06 | — | — | EP | claimed |