SCHEMBL4544218

SCHEMBL4544218

CC=CCc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 1/20 0.61
CTSB P07858 1/20 0.61
MMP9 P14780 1/20 0.61
DNMT1 P26358 1/20 0.61
DNMT3B Q9UBC3 1/20 0.61
DNMT3L Q9UJW3 1/20 0.61
DNMT3A Q9Y6K1 1/20 0.61
LCK P06239 2/20 0.56
HNF4A P41235 2/20 0.54
KAT8 Q9H7Z6 2/20 0.53
MCL1 Q07820 4/20 0.49
EGFR P00533 1/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 3/20 0.49
HSD17B10 Q99714 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
PTGS2 P35354 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9617815 0.81 KLKB1 (0.57) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL979252 0.79 KLKB1 (0.65) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL9742483 0.78 XDH (0.59) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL30957054 0.78 XDH (0.59) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL9742479 0.78 XDH (0.59) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL9159293 0.78 KLKB1 (0.57) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL9159301 0.78 KLKB1 (0.57) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL14053314 0.77 GABRA1 (0.60) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL8815944 0.77 KLKB1 (0.71) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL418713 0.77 KLKB1 (0.71) KLKB1CTSBMMP9DNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629302-B2 Lubricating oil additive and lubricating oil composition NIPPON OIL CORPORATION (JP) 2009-12-08 US disclosed
US-20060063686-A1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORPORATION (JP) 2006-03-23 US disclosed
EP-1580257-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2005-09-28 EP disclosed