Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.71 |
| ▸ | CTSB | P07858 | 1/20 | 0.71 |
| ▸ | MMP9 | P14780 | 1/20 | 0.71 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.71 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.71 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.71 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.71 |
| ▸ | LCK | P06239 | 2/20 | 0.65 |
| ▸ | HNF4A | P41235 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846227 | 1.00 | KLKB1 (0.71) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL31236856 | 0.85 | LCK (0.71) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL702567 | 0.84 | ALDH1A1 (0.57) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL8815955 | 0.84 | KLKB1 (0.51) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL6451619 | 0.83 | ALDH1A1 (0.52) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL10950033 | 0.83 | LCK (0.89) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL29414416 | 0.83 | KLKB1 (1.00) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL160646 | 0.83 | KLKB1 (1.00) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| Hydrochloric Acid SCHEMBL6289406 | 0.82 | ALDH1A1 (0.55) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL21632307 | 0.82 | PLG (0.49) | KLKB1CTSBMMP9DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012903-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR INHIBITING THE BINDING OF PROTEINS CONTAINING AN SH2 DOMAIN TO COGNATE PHOSPHORYLATED PROTEINS | WARNER-LAMBERT COMPANY (US) | 1997-04-10 | — | — | WO | disclosed |