Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL4140225 | 0.98 | FDPS (0.39) | FDPSBLMTDP1BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL3175309 | 0.90 | FDPS (0.53) | FDPSBLMTDP1 | |
| Triphosphate SCHEMBL153616 | 0.88 | FDPS (0.32) | FDPSBLMTDP1BTN3A1 | |
| Triphosphate SCHEMBL27789890 | 0.86 | TDP1 (0.43) | FDPSBLMTDP1BTN3A1 | |
| Triphosphate SCHEMBL12541906 | 0.85 | FDPS (0.30) | FDPSBLMTDP1 | |
| Pyrimidine SCHEMBL29228083 | 0.84 | BTN3A1 (0.39) | FDPSBLMTDP1BTN3A1 | |
| Triphosphate SCHEMBL28958469 | 0.84 | TDP1 (0.41) | FDPSBLMTDP1BTN3A1 | |
| Pyrimidine SCHEMBL27738489 | 0.82 | FDPS (0.38) | FDPSBLMTDP1 | |
| Pyrimidine SCHEMBL988740 | 0.79 | FDPS (0.34) | FDPSTDP1BTN3A1 | |
| Pyrimidine SCHEMBL4154828 | 0.79 | FDPS (0.34) | FDPSTDP1BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106939336-A | The method for detecting oxidative damage DNA | 国家体育总局体育科学研究所 | 2017-07-11 | — | — | CN | claimed |
| CN-103031287-B | Cordyceps Chinese Hirsutella nucleoside diphosphokinase, coding gene and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2014-12-10 | — | — | CN | claimed |
| CN-103031287-A | Cordyceps Chinese Hirsutella nucleoside diphosphokinase, coding gene and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2013-04-10 | — | — | CN | claimed |
| US-7612047-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | claimed |
| CN-101495497-A | Process for producing di (pyrimidine nucleoside 5' -) polyphosphate | YAMASA CORP (JP) | 2009-07-29 | — | — | CN | claimed |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | DOUGLASS III JAMES G | 2009-03-19 | — | — | US | claimed |
| US-20030055235-A1 | Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and \"unnatural\" UDP- and TDP-nucleotide sugars | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2003-03-20 | — | — | US | claimed |
| WO-2002048331-A2 | ACTIVE-SITE ENGINEERING OF NUCLEOTIDYLTRANSFERASES AND ENZYMATIC METHODS FOR THE SYNTHESIS OF NATURAL AND 'UNNATURAL' UDP- AND NUCLEOTIDE SUGARS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2002-06-20 | — | — | WO | claimed |
| CN-108368542-A | For genome assembling, the method for the fixed detection of nucleic acids mutually and independently of target of haplotype | 多弗泰尔基因组学有限责任公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-103392008-B | Movement by continuation enzyme with the precision controlling DNA of a nucleotides in nano-pore | 加利福尼亚大学董事会 | 2017-10-20 | — | — | CN | disclosed |
| CN-106939336-A | The method for detecting oxidative damage DNA | 国家体育总局体育科学研究所 | 2017-07-11 | — | — | CN | disclosed |
| CN-104250645-B | RNA fragment and preparation method and application thereof | 昆山彭济凯丰生物科技有限公司 | 2017-05-03 | — | — | CN | disclosed |
| EP-2935664-A1 | STABILIZED NANOPORE AND MICROPORE STRUCTURES AND METHODS FOR MAKING AND USING THE SAME | Ibis Biosciences, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| CN-102159949-B | Multi-ligand capture agents and related compositions, methods and systems | CALIFORNIA INST OF TECHN | 2015-03-04 | — | — | CN | disclosed |
| US-6111074-A | AMINO ACID SEQUENCE OF POLYPEPTIDE FROM THE URIDINE MONOPHOSPHATE KINASE FAMILY; FOR SCREENING BACTERICIDES AND BACTERIOSTATS; FOR DIAGNOSIS AND PROPHYLAXIS OF INFECTIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |
| US-5830653-A | ABILITY TO INHIBIT GENE EXPRESSION | GILEAD SCIENCES, INC. (US) | 1998-11-03 | — | — | US | disclosed |
| US-5645985-A | USED FOR DIAGNOSIS TO DETECT VIRUSES OR DISEASED CONDITIONS | GILEAD SCIENCES, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0637965-A4 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES. | GILEAD SCIENCES INC (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0637965-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1995-02-15 | — | — | EP | disclosed |
| WO-1993010820-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055235-A1 | Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and \"unnatural\" UDP- and TDP-nucleotide sugars | PNP, NUDT14, ENTPD5 | FDPS 124/4885BLM 2094/4885TDP1 43/4885 |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | PNKP, ENTPD5, ENPP1 | FDPS 184/4885BLM 454/4885TDP1 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.