Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544465 | 0.87 | S1PR1 (0.45) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL4544487 | 0.86 | RAB9A (0.44) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL1025831 | 0.84 | AAK1 (0.39) | PTGS2AAK1MAPTTP53HDAC6 | |
| SCHEMBL4544505 | 0.82 | ESR1 (0.41) | MAPTTP53HDAC6KDM4ENPC1 | |
| SCHEMBL4544467 | 0.81 | ALOX5 (0.59) | AAK1MAPTTP53HDAC6KDM4E | |
| SCHEMBL11964150 | 0.81 | RAB9A (0.44) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL4544472 | 0.81 | MAPT (0.43) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL1026787 | 0.76 | AAK1 (0.41) | PTGS2AAK1MAPTTP53HDAC6 | |
| SCHEMBL4544531 | 0.76 | PIK3CB (0.54) | MAPTTP53HDAC6KDM4ENPC1 | |
| SCHEMBL1025661 | 0.76 | F2RL3 (0.47) | PTGS2AAK1MAPTTP53HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8445522-B2 | Substituted 2-(4-pyridyl)benzoxazoles, and compositions thereof, for use in arthropod pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8324387-B2 | Substituted Oxazolo[5,4-b]pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-18 | — | — | US | disclosed |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120245167-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
| US-8242133-B2 | Arthropod pest control compositions comprising substituted oxazolo [5,4-b ] pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120108586-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20110039843-A1 | HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245167-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | C5, C1S, C1R | PTGS2 2089/4885AAK1 748/4885MAPT 4616/4885 |
| US-20120108586-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | C5, C1S, C1R | PTGS2 2089/4885AAK1 748/4885MAPT 4616/4885 |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | PTGS2 1731/4885AAK1 1659/4885MAPT 2543/4885 |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | NISCH, DDT, AADAC | PTGS2 2213/4885AAK1 1698/4885MAPT 3078/4885 |
| US-20110039843-A1 | HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND | C5, C9, C1S | PTGS2 3002/4885AAK1 1276/4885MAPT 4448/4885 |
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | CYC1, C9, C5 | PTGS2 1657/4885AAK1 1525/4885MAPT 4631/4885 |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | PTGS2 1367/4885AAK1 1838/4885MAPT 2518/4885 |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, AADAC, CYP4F3 | PTGS2 790/4885AAK1 1579/4885MAPT 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.