Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31510258 | 1.00 | MAPK1 (0.56) | MAPK1GPR35TP53HPGDTSHR | |
| SCHEMBL9318675 | 0.87 | ALDH1A1 (0.44) | MAPK1GPR35TP53HPGDTSHR | |
| SCHEMBL23144771 | 0.85 | GPR35 (0.56) | MAPK1GPR35TP53HPGDTSHR | |
| SCHEMBL7028658 | 0.85 | MAPK1 (0.60) | MAPK1GPR35TP53HPGDTSHR | |
| SCHEMBL13346846 | 0.83 | GPR35 (0.58) | MAPK1GPR35TP53HPGDTSHR | |
| SCHEMBL3953683 | 0.81 | ALDH1A1 (0.51) | MAPK1GPR35TP53HPGDTSHR | |
| SCHEMBL27496923 | 0.80 | MAPK1 (0.55) | MAPK1GPR35TP53HPGDTSHR | |
| SCHEMBL11193900 | 0.80 | MAPT (0.52) | MAPK1GPR35TP53HPGDTSHR | |
| SCHEMBL11039924 | 0.79 | TSHR (0.56) | MAPK1TSHRSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL11189545 | 0.79 | MAPK1 (0.53) | MAPK1GPR35TP53HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234554-A2 | CRYSTALLINE SOLID FORMS OF A BET INHIBITOR | Incyte Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3472157-B1 | CRYSTALLINE SOLID FORMS OF A BET INHIBITOR | INCYTE CORP (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-106065009-A | As the compound of hepatitis c inhibitor and the application in medicine thereof | 广东东阳光药业有限公司 | 2016-11-02 | — | — | CN | disclosed |
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8445522-B2 | Substituted 2-(4-pyridyl)benzoxazoles, and compositions thereof, for use in arthropod pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8324387-B2 | Substituted Oxazolo[5,4-b]pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-18 | — | — | US | disclosed |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5219874-A | Heterocyclic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-15 | — | — | US | disclosed |
| EP-0526093-A1 | New non-steroidal agents as 5-alpha reductase inhibitors | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1992018132-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA COMTAINING A 5 ALPHA-REDUCTASE INHIBITOR | MERCK & CO., INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992016213-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |
| WO-1992016233-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC CANCER CONTAINING A 5 ALPHA REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |
| EP-0482771-A2 | Heterocyclic acids | ZENECA LIMITED (GB) | 1992-04-29 | — | — | EP | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | MAPK1 4224/4885GPR35 3737/4885TP53 4304/4885 |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | NISCH, DDT, AADAC | MAPK1 4483/4885GPR35 2308/4885TP53 4670/4885 |
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | CYC1, C9, C5 | MAPK1 953/4885GPR35 3572/4885TP53 3500/4885 |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | MAPK1 4628/4885GPR35 2440/4885TP53 4239/4885 |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, AADAC, CYP4F3 | MAPK1 4201/4885GPR35 2487/4885TP53 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.