SCHEMBL4544807

SCHEMBL4544807

COC(=O)/C(C#N)=C\C=C\N1CCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RECQL P46063 1/20 0.50
▸ APP P05067 2/20 0.43
▸ KMT2A Q03164 6/20 0.40
▸ POLB P06746 1/20 0.38
▸ ALDH1A1 P00352 7/20 0.38
▸ KDM4E B2RXH2 4/20 0.38
▸ MEN1 O00255 2/20 0.37
▸ ADORA2A P29274 1/20 0.37
▸ ADORA2B P29275 1/20 0.37
▸ ADORA1 P30542 1/20 0.37
▸ MAPT P10636 3/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ SENP8 Q96LD8 1/20 0.36
▸ SENP7 Q9BQF6 1/20 0.36
▸ SENP6 Q9GZR1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12310408 0.98 RECQL (0.49) RECQLAPPKMT2APOLBALDH1A1
SCHEMBL12294071 0.88 RECQL (0.68) RECQLAPPKMT2APOLBALDH1A1
SCHEMBL23140711 0.88 RECQL (0.68) RECQLAPPKMT2APOLBALDH1A1
SCHEMBL23140710 0.88 RECQL (0.68) RECQLAPPKMT2APOLBALDH1A1
SCHEMBL15761683 0.79 APP (0.54) RECQLAPPKMT2AALDH1A1KDM4E
SCHEMBL12292371 0.78 MAPT (0.44) RECQLAPPKMT2AALDH1A1KDM4E
SCHEMBL12310405 0.78 KMT2A (0.46) RECQLKMT2APOLBALDH1A1KDM4E
SCHEMBL14629850 0.78 KMT2A (0.46) RECQLKMT2APOLBALDH1A1KDM4E
SCHEMBL21470217 0.78 ALDH1A1 (0.40) RECQLAPPKMT2AALDH1A1KDM4E
SCHEMBL14095058 0.78 RECQL (0.72) RECQLAPPKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 — — US disclosed
US-20090080074-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-03-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090080074-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE RPA3, RTF1, RPA1 RECQL 328/4885APP 1275/4885KMT2A 3282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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