SCHEMBL4547558

SCHEMBL4547558

COc1ccc(Nc2nc(Nc3cccc(CO)c3)nc(Nc3cccc(OC)c3)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 4/20 0.55
MEN1 O00255 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
KMT2A Q03164 2/20 0.53
PIK3CA P42336 1/20 0.51
PIK3CB P42338 1/20 0.51
PIK3CG P48736 1/20 0.51
APP P05067 1/20 0.51
VSIR Q9H7M9 1/20 0.51
GBA1 P04062 1/20 0.51
ALDH1A1 P00352 1/20 0.50
GAA P10253 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
POLB P06746 1/20 0.50
KDM4E B2RXH2 1/20 0.49
HTT P42858 1/20 0.49
TAAR1 Q96RJ0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4547557 0.93 KCNH3 (0.53) KCNH3NPC1RAB9AVSIRGBA1
SCHEMBL14184957 0.91 APP (0.50) KCNH3MEN1NPC1RAB9AKMT2A
SCHEMBL4547556 0.89 KCNH3 (0.54) KCNH3MEN1NPC1RAB9AKMT2A
SCHEMBL4544829 0.88 KCNH3 (0.68) KCNH3MEN1NPC1RAB9AKMT2A
SCHEMBL4547449 0.88 EGFR (0.55) KCNH3MEN1NPC1RAB9AKMT2A
SCHEMBL4547555 0.84 KCNH3 (0.50) KCNH3MEN1NPC1RAB9AKMT2A
SCHEMBL4547570 0.84 ALDH1A1 (0.50) KCNH3MEN1NPC1RAB9AKMT2A
SCHEMBL4547448 0.83 SIRT1 (0.49) KCNH3MEN1NPC1RAB9AKMT2A
SCHEMBL14810930 0.83 RORC (0.46) KCNH3MEN1KMT2AVSIRALDH1A1
SCHEMBL14583170 0.83 KCNH3 (0.59) KCNH3MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8395727-B2 VA mode liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-8350999-B2 Liquid-crystal display device having particular retardations and internal hazes FUJIFILM CORPORATION (JP) 2013-01-08 US disclosed
US-20120236233-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236234-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120229734-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-8203675-B2 Liquid-crystal display device having retardation films with different optical anisotropy FUJIFILM CORPORATION (JP) 2012-06-19 US disclosed
US-20120120348-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-05-17 US disclosed
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 US disclosed
US-7990502-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-20090066887-A1 Polymer Film, Polarizing Plate Protective Film, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
US-20080226888-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed