SCHEMBL4544834

SCHEMBL4544834

COc1cccc(Nc2nc(Nc3ccccc3)nc(Nc3cccc(OC)c3)n2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 2/20 0.70
EGFR P00533 1/20 0.61
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
MAPT P10636 3/20 0.60
TP53 P04637 2/20 0.60
MAPK1 P28482 1/20 0.60
ADORA2A P29274 1/20 0.59
ADORA1 P30542 1/20 0.59
POLB P06746 3/20 0.58
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
HTT P42858 2/20 0.57
SYK P43405 1/20 0.57
TSHR P16473 1/20 0.57
KDM4E B2RXH2 1/20 0.56
TAAR1 Q96RJ0 1/20 0.56
ABCG2 Q9UNQ0 3/20 0.56
ABCB1 P08183 2/20 0.56
PIK3CA P42336 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544861 1.00 KCNH3 (0.70) KCNH3EGFRMEN1KMT2AMAPT
SCHEMBL13999983 0.94 KCNH3 (0.63) KCNH3EGFRMEN1KMT2AMAPT
SCHEMBL4544829 0.92 KCNH3 (0.68) KCNH3EGFRMEN1KMT2AMAPT
SCHEMBL4544832 0.89 KCNH3 (0.65) KCNH3EGFRMEN1KMT2AMAPT
SCHEMBL4544869 0.89 KCNH3 (0.58) KCNH3EGFRMEN1KMT2AMAPT
SCHEMBL28736393 0.88 KCNH3 (0.68) KCNH3EGFRMEN1KMT2AMAPT
SCHEMBL917608 0.87 MTNR1B (0.65) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL30080139 0.87 MTNR1B (0.65) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL4544763 0.87 KCNH3 (0.67) KCNH3EGFRMEN1KMT2AMAPT
SCHEMBL4544822 0.87 KCNH3 (0.67) KCNH3EGFRMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-20150253480-A1 RETARDATION FILM, ELONGATED CIRCULARLY POLARIZING PLATE AND ORGANIC EL DISPLAY PRODUCED USING SAID RETARDATION FILM Konica Minolta, Inc. (JP) 2015-09-10 US disclosed
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
US-9103988-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-08-11 US disclosed
US-8976325-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-8947621-B2 Liquid crystal display device comprising a front plate having a lamda/4 plate that includes a hard coat layer and method for manufacturing the same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2015-02-03 US disclosed
US-8681295-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-03-25 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-20130169897-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-07-04 US disclosed
US-8477273-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed