Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544977 | 0.80 | TSHR (0.46) | ALDH1A1TSHRHCAR2NAAARAD52 | |
| SCHEMBL4544983 | 0.80 | TSHR (0.46) | ALDH1A1TSHRHCAR2NAAARAD52 | |
| SCHEMBL4544971 | 0.80 | TSHR (0.46) | ALDH1A1TSHRHCAR2NAAARAD52 | |
| SCHEMBL4544980 | 0.80 | TSHR (0.46) | ALDH1A1TSHRHCAR2NAAARAD52 | |
| SCHEMBL4544972 | 0.80 | TSHR (0.46) | ALDH1A1TSHRHCAR2NAAARAD52 | |
| SCHEMBL4544974 | 0.76 | HCAR2 (0.34) | ALDH1A1HCAR2LMNASMN1; SMN2 | |
| SCHEMBL4544960 | 0.74 | TSHR (0.54) | ALDH1A1TSHRHCAR2NAAAESR1 | |
| SCHEMBL4544970 | 0.74 | TSHR (0.54) | ALDH1A1TSHRHCAR2NAAAESR1 | |
| SCHEMBL4544985 | 0.74 | TSHR (0.50) | ALDH1A1TSHRHCAR2NAAARAD52 | |
| SCHEMBL4544978 | 0.74 | TSHR (0.46) | ALDH1A1TSHRHCAR2NAAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298736-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8178267-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090291381-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291377-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090233207-A1 | PYRAZOLOTRIAZOLE COMPOUND AND ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233207-A1 | PYRAZOLOTRIAZOLE COMPOUND AND ELECTROPHOTOGRAPHIC TONER | HAX1, XDH, GLRX3 | ALDH1A1 3741/4885ATM 4284/4885TSHR 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.