SCHEMBL454605

SCHEMBL454605

CCN(Cc1ccccc1)C(O)Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
SIGMAR1 Q99720 1/20 0.46
TRPA1 O75762 2/20 0.46
OPRK1 P41145 2/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2A P28223 1/20 0.46
SLC6A4 P31645 1/20 0.46
ADRA1A P35348 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KCNH2 Q12809 1/20 0.46
TSHR P16473 3/20 0.44
HPGD P15428 1/20 0.44
ALDH1A1 P00352 2/20 0.42
MGLL Q99685 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TP53 P04637 1/20 0.41
BCHE P06276 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11070459 0.90 TRPA1 (0.50) LMNASIGMAR1TRPA1OPRK1ADRA2B
SCHEMBL9380682 0.87 LMNA (0.46) LMNASIGMAR1TRPA1ADRA2BHTR2A
SCHEMBL1302289 0.81 TSHR (0.52) LMNASIGMAR1TRPA1OPRK1ADRA2B
SCHEMBL10961664 0.80 NPSR1 (0.46) LMNASIGMAR1TRPA1OPRK1ADRA2B
SCHEMBL4432874 0.79 TSHR (0.46) LMNASIGMAR1TRPA1OPRK1ADRA2B
SCHEMBL10960394 0.77 ADRA2B (0.63) SIGMAR1TRPA1OPRK1ADRA2BADRA2C
SCHEMBL12124877 0.76 TSHR (0.50) LMNASIGMAR1OPRK1ADRA2BADRA2C
SCHEMBL7050937 0.76 TSHR (0.48) LMNAOPRK1ADRA2BADRA2CSLC6A2
SCHEMBL14491043 0.75 TRPA1 (0.56) LMNASIGMAR1TRPA1OPRK1ADRA2B
SCHEMBL14491045 0.75 TRPA1 (0.56) LMNASIGMAR1TRPA1OPRK1ADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871317-B2 Curable adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2014-10-28 US disclosed
EP-2613933-A2 CURABLE ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH Teknor Apex Company (US) 2013-07-17 EP disclosed
US-20120064274-A1 Curable adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2012-03-15 US disclosed
WO-2012033519-A2 CURABLE ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH TEKNOR APEX COMPANY (US) 2012-03-15 WO disclosed