Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116745 | 0.88 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL10664892 | 0.81 | ACHE (0.37) | ALDH1A1CYP19A1NQO2 | |
| SCHEMBL13175227 | 0.81 | — | — | |
| SCHEMBL2111129 | 0.79 | — | — | |
| SCHEMBL192045 | 0.79 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL192671 | 0.79 | CA2 (0.33) | — | |
| SCHEMBL8830029 | 0.79 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1AGXT | |
| SCHEMBL193574 | 0.79 | CA2 (0.33) | — | |
| SCHEMBL9784645 | 0.78 | — | — | |
| SCHEMBL8500418 | 0.76 | SMN1; SMN2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114184699-B | Method for determining potential genotoxic impurities in esomeprazole sodium by liquid chromatography-mass spectrometry | 北京悦康科创医药科技股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-110317164-B | Preparation method of omeprazole intermediate | 抚州三和医药化工有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-114184699-A | Method for determining potential genotoxic impurities in esomeprazole sodium by liquid chromatography-mass spectrometry | 北京悦康科创医药科技股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114044752-A | Production method of omeprazole drug intermediate 2-chloromethyl-3, 5-dimethyl-4-methoxypyridine hydrochloride | 上海卓鼎生物技术有限公司 | 2022-02-15 | — | — | CN | claimed |
| CN-111943883-A | Production process of Orimei chloride | 抚州三和医药化工有限公司 | 2020-11-17 | — | — | CN | claimed |
| US-5292886-A | Process for the preparation of 2-halomethyl-3,5-dimethyl-4-methoxypyridine halohydrate | ESTEVE QUIMICA, S.A., A CORP. OF SPAIN (ES) | 1994-03-08 | — | — | US | claimed |
| CN-110317164-B | Preparation method of omeprazole intermediate | 抚州三和医药化工有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114044752-A | Production method of omeprazole drug intermediate 2-chloromethyl-3, 5-dimethyl-4-methoxypyridine hydrochloride | 上海卓鼎生物技术有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-112645873-A | Synthetic method of 4-methoxy-2, 3, 5-trimethyl-pyridine nitrogen oxide | 荆楚理工学院 | 2021-04-13 | — | — | CN | disclosed |
| CN-111943883-A | Production process of Orimei chloride | 抚州三和医药化工有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-111943883-A | Production process of Orimei chloride | 抚州三和医药化工有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-111303018-A | Synthetic method of omeprazole intermediate | 浙江华洲药业有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-110317164-A | A kind of preparation method of intermediate of omeprazole | 抚州三和医药化工有限公司 | 2019-10-11 | — | — | CN | disclosed |
| EP-0226558-A2 | Chemical intermediates and methods for their preparation | Aktiebolaget Hässle (SE) | 1987-06-24 | — | — | EP | disclosed |
| US-4634710-A | ANTIULCER, ANTISECRETORY | HOFFMANN-LA ROCHE INC. (US) | 1987-01-06 | — | — | US | disclosed |
| US-4620008-A | Processes for the preparation of omeprazole and intermediates therefore | AKTIEBOLAGET HASSLE (SE) | 1986-10-28 | — | — | US | disclosed |
| US-4560693-A | ANTISECRETORY, ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-12-24 | — | — | US | disclosed |
| US-4544750-A | Certain pyridyl-N-oxide intermediates for the preparation of omeprazole | AKTIEBOLAGET HASSLE (SE) | 1985-10-01 | — | — | US | disclosed |
| US-4472409-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-18 | — | — | US | disclosed |
| EP-0103553-A1 | Intermediates for the preparation of omeprazole | Aktiebolaget Hässle (SE) | 1984-03-21 | — | — | EP | disclosed |