SCHEMBL4546283

SCHEMBL4546283

CC1O[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C(OC(=O)c2ccccc2)[C@@H](C)[C@@H]1C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 1/20 0.37
LGALS1 P09382 1/20 0.37
LGALS3 P17931 1/20 0.37
LGALS7; LGALS7B P47929 1/20 0.37
PTGES2 Q9H7Z7 1/20 0.35
ABCB1 P08183 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GAA P10253 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
BCHE P06276 1/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
PTPN1 P18031 1/20 0.32
SELP P16109 3/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17590141 0.86 LGALS9 (0.33) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTGES2
SCHEMBL4546317 0.86 LGALS9 (0.33) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTGES2
SCHEMBL11981202 0.85 USP2 (0.41) LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1
SCHEMBL16812944 0.84 LGALS9 (0.42) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTGES2
SCHEMBL12618618 0.84 LGALS9 (0.42) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTGES2
SCHEMBL4546286 0.78
SCHEMBL16812938 0.77 LGALS9 (0.43) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTGES2
SCHEMBL26823580 0.77 LGALS9 (0.43) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTGES2
SCHEMBL16812935 0.77 LGALS9 (0.43) LGALS9LGALS1LGALS3LGALS7; LGALS7BPTGES2
SCHEMBL18385957 0.76 LGALS9 (0.44) LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987430-B2 Efficient and scalable process for the manufacture of fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2015-03-24 US disclosed
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-10-03 US disclosed
US-8420790-B2 Efficient and scalable process for the manufacture of Fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-16 US disclosed
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 LGALS9 1981/4885LGALS1 2590/4885LGALS3 1861/4885
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 LGALS9 1981/4885LGALS1 2590/4885LGALS3 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.