SCHEMBL4546317

SCHEMBL4546317

CC(=O)CCC(=O)O[C@@H]1C(C)O[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C(OC(=O)c2ccccc2)[C@H]1C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 1/20 0.33
LGALS1 P09382 1/20 0.33
LGALS3 P17931 1/20 0.33
LGALS7; LGALS7B P47929 1/20 0.33
ABCB1 P08183 5/20 0.32
PTGES2 Q9H7Z7 1/20 0.31
SELP P16109 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17590141 1.00 LGALS9 (0.33) LGALS9LGALS1LGALS3LGALS7; LGALS7BABCB1
SCHEMBL4546311 0.89 LGALS8 (0.31)
SCHEMBL17590144 0.89 LGALS8 (0.31)
SCHEMBL4546283 0.86 LGALS9 (0.37) LGALS9LGALS1LGALS3LGALS7; LGALS7BABCB1
SCHEMBL17590142 0.79 ABCB1 (0.33) LGALS9LGALS1LGALS3LGALS7; LGALS7BABCB1
SCHEMBL4546312 0.79 ABCB1 (0.33) LGALS9LGALS1LGALS3LGALS7; LGALS7BABCB1
SCHEMBL11981202 0.79 USP2 (0.41) LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL4546306 0.79 LGALS9 (0.40) LGALS9LGALS1LGALS3LGALS7; LGALS7BABCB1
SCHEMBL17590139 0.79 LGALS9 (0.40) LGALS9LGALS1LGALS3LGALS7; LGALS7BABCB1
SCHEMBL17590157 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987430-B2 Efficient and scalable process for the manufacture of fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2015-03-24 US disclosed
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-10-03 US disclosed
US-20130102764-A1 PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-25 US disclosed
US-8420790-B2 Efficient and scalable process for the manufacture of Fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-16 US disclosed
US-8288515-B2 Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-10-16 US disclosed
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-05-10 US disclosed
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF F11, TFPI, STS LGALS9 1800/4885LGALS1 2643/4885LGALS3 2242/4885
US-20130102764-A1 PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF TFPI, PLG, PCSK6 LGALS9 780/4885LGALS1 1318/4885LGALS3 1258/4885
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 LGALS9 1981/4885LGALS1 2590/4885LGALS3 1861/4885
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 LGALS9 1981/4885LGALS1 2590/4885LGALS3 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.