SCHEMBL4546501

SCHEMBL4546501

COc1cc(/C=C/c2cc(OCCC(C)CCCC(C)C)c(/C=C/c3cc(OC)c(C)cc3OC)cc2OC)c(OC)cc1C

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP1A1 P04798 2/20 0.33
CYP1B1 Q16678 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
CYP1A2 P05177 1/20 0.33
LMNA P02545 1/20 0.33
ESR1 P03372 1/20 0.33
PDPK1 O15530 1/20 0.32
ALOX5 P09917 1/20 0.32
FDPS P14324 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
NFE2L2 Q16236 1/20 0.31
TLR8 Q9NR97 1/20 0.31
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12884188 0.92 HMGCR (0.42) HMGCRCYP3A4TRPV1LMNAESR1
SCHEMBL18804474 0.91 HMGCR (0.44) HMGCRCYP3A4TRPV1LMNAESR1
Hydrochloric Acid SCHEMBL3124253 0.88 LMNA (0.38) TRPV1LMNAESR1PDPK1ALOX5
Hydrochloric Acid SCHEMBL3124250 0.88 LMNA (0.38) TRPV1LMNAESR1PDPK1ALOX5
SCHEMBL11957249 0.86 HTR2A (0.37) LMNATAAR1
SCHEMBL13016850 0.83 LMNA (0.45) CYP3A4LMNAESR1ALOX5FDPS
SCHEMBL13017290 0.83 APP (0.34) CYP1A1CYP1B1CYP1A2ESR1ALOX5
SCHEMBL4581149 0.82 TRPV1 (0.37) CYP3A4TRPV1LMNAALOX5FDPS
SCHEMBL1203769 0.82 ALDH1A1 (0.49) CYP3A4TRPV1LMNAALOX5FDPS
SCHEMBL13393975 0.81 TRPV1 (0.32) HMGCRCYP3A4CYP1A1CYP1B1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10333068-B2 White light emission MERCK PATENT GMBH (DE) 2019-06-25 US disclosed
US-20170179392-A1 WHITE LIGHT EMISSION MERCK PATENT GMBH (DE) 2017-06-22 US disclosed
US-20170179392-A1 WHITE LIGHT EMISSION MERCK PATENT GMBH (DE) 2017-06-22 US disclosed
US-20120104380-A1 CONDUCTING FORMULATION MERCK PATENT GMBH (DE) 2012-05-03 US disclosed