Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | C5 | P01031 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL489290 | 0.87 | ALOX5 (0.38) | TRPV1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL1203769 | 0.86 | ALDH1A1 (0.49) | TRPV1LMNAKMT2ACYP3A4ALOX15 | |
| SCHEMBL1304615 | 0.85 | ALOX5 (0.39) | TRPV1LMNAFDPSALOX5GAA | |
| SCHEMBL4563455 | 0.83 | ALOX5 (0.41) | LMNAKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL4546501 | 0.82 | HMGCR (0.34) | TRPV1LMNACYP3A4FDPSALOX5 | |
| SCHEMBL11957249 | 0.81 | HTR2A (0.37) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7133337 | 0.81 | ALOX5 (0.43) | LMNAKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL18804474 | 0.79 | HMGCR (0.44) | TRPV1LMNACYP3A4ALOX5KDM4E | |
| SCHEMBL4430873 | 0.79 | LMNA (0.41) | TRPV1LMNAFDPSALOX5TLR8 | |
| SCHEMBL12884188 | 0.78 | HMGCR (0.42) | TRPV1LMNACYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402717-B2 | Method for producing olefin-substituted aromatic or heteroaromatic compounds | MERCK PATENT GMBH (DE) | 2008-07-22 | — | — | US | disclosed |
| EP-1307413-B1 | METHOD FOR PRODUCING OLEFIN-SUBSTITUTED AROMATIC OR HETEROAROMATIC COMPOUNDS | COVION ORGANIC SEMICONDUCTORS (DE) | 2005-04-27 | — | — | EP | disclosed |
| US-20040254388-A1 | Method for producing olefin-substituted aromatic or heteroaromatic compounds | MERCK PATENT GMBH (DE) | 2004-12-16 | — | — | US | disclosed |
| EP-1307413-A1 | METHOD FOR PRODUCING OLEFIN-SUBSTITUTED AROMATIC OR HETEROAROMATIC COMPOUNDS | Covion Organic Semiconductors GmbH (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002010093-A1 | METHOD FOR PRODUCING OLEFIN-SUBSTITUTED AROMATIC OR HETEROAROMATIC COMPOUNDS | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-02-07 | — | — | WO | disclosed |