⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223715 | 0.77 | — | — | |
| SCHEMBL7197761 | 0.67 | — | — | |
| SCHEMBL2435080 | 0.65 | ALDH1A1 (0.40) | — | |
| SCHEMBL121521 | 0.63 | — | — | |
| SCHEMBL7332054 | 0.63 | — | — | |
| SCHEMBL11977449 | 0.61 | — | — | |
| SCHEMBL828997 | 0.61 | — | — | |
| SCHEMBL75265 | 0.61 | — | — | |
| SCHEMBL1025859 | 0.61 | — | — | |
| SCHEMBL13864475 | 0.61 | PNMT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230190-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| US-11807618-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2023-11-07 | — | — | US | disclosed |
| US-20220213053-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-07-07 | — | — | US | disclosed |
| EP-3562818-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-05-18 | — | — | EP | disclosed |
| US-11279683-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2022-03-22 | — | — | US | disclosed |
| CN-110114349-B | Thiophene derivatives as antiviral agents | 埃尼奥制药公司 | 2022-03-15 | — | — | CN | disclosed |
| US-20190352275-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2019-11-21 | — | — | US | disclosed |
| EP-3562818-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | Enyo Pharma (FR) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018122317-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2018-07-05 | — | — | WO | disclosed |
| US-20150249214-A1 | CONJUGATED POLYMER, AND ELECTRON DONATING ORGANIC MATERIAL, MATERIAL FOR PHOTOVOLTAIC DEVICE AND PHOTOVOLTAIC DEVICE USING THE CONJUGATED POLYMER | TORAY INDUSTRIES, INC. (JP) | 2015-09-03 | — | — | US | disclosed |
| US-20150249214-A1 | CONJUGATED POLYMER, AND ELECTRON DONATING ORGANIC MATERIAL, MATERIAL FOR PHOTOVOLTAIC DEVICE AND PHOTOVOLTAIC DEVICE USING THE CONJUGATED POLYMER | TORAY INDUSTRIES, INC. (JP) | 2015-09-03 | — | — | US | disclosed |
| US-8168671-B2 | Synthesis of thieno[3,4-b]thiophene, thieno[3,4-b]furan, related compounds and their derivatives and use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2012-05-01 | — | — | US | disclosed |
| US-8168671-B2 | Synthesis of thieno[3,4-b]thiophene, thieno[3,4-b]furan, related compounds and their derivatives and use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090326187-A1 | SYNTHESIS OF THIENO[3,4-b]THIOPHENE, THIENO[3,4-b]FURAN, RELATED COMPOUNDS AND THEIR DERIVATIVES AND USE THEREOF | THE UNIVERSITY OF CONNECTICUT | 2009-12-31 | — | — | US | disclosed |
| US-20090326187-A1 | SYNTHESIS OF THIENO[3,4-b]THIOPHENE, THIENO[3,4-b]FURAN, RELATED COMPOUNDS AND THEIR DERIVATIVES AND USE THEREOF | THE UNIVERSITY OF CONNECTICUT | 2009-12-31 | — | — | US | disclosed |
| US-5304657-A | Insecticides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-04-19 | — | — | US | disclosed |