⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485508 | 0.97 | PNMT (0.48) | — | |
| SCHEMBL15281530 | 0.97 | PNMT (0.48) | — | |
| SCHEMBL15276726 | 0.97 | PNMT (0.48) | — | |
| SCHEMBL15278765 | 0.97 | PNMT (0.48) | — | |
| SCHEMBL828997 | 0.94 | — | — | |
| Oxalic Acid SCHEMBL4777724 | 0.87 | ALDH1A1 (0.44) | — | |
| SCHEMBL562638 | 0.82 | — | — | |
| SCHEMBL19135901 | 0.79 | DRD2 (0.42) | — | |
| SCHEMBL19674177 | 0.79 | PNMT (0.38) | — | |
| SCHEMBL19135935 | 0.77 | PNMT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3446 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296926-A1 | SELECTIVE LIGANDS FOR MODULATION OF GIRK CHANNELS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2025-09-25 | — | — | US | claimed |
| US-12351574-B2 | Selective ligands for modulation of GIRK channels | NORTHEASTERN UNIVERSITY (US) | 2025-07-08 | — | — | US | claimed |
| CN-120021621-A | Application of 4,5,6, 7-tetrahydrobenzothiophene compounds in pest control | 中国农业大学 | 2025-05-23 | — | — | CN | claimed |
| WO-2025101127-A1 | CONJUGATED OLIGOELECTROLYTES AND METHODS STAINING MITOCHONDRIA THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2025-05-15 | — | — | WO | claimed |
| US-20240199591-A1 | SELECTIVE LIGANDS FOR MODULATION OF GIRK CHANNELS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2024-06-20 | — | — | US | claimed |
| US-11952370-B2 | Selective ligands for modulation of GIRK channels | NORTHEASTERN UNIVERSITY (US) | 2024-04-09 | — | — | US | claimed |
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | claimed |
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | claimed |
| US-20210253561-A1 | SELECTIVE LIGANDS FOR MODULATION OF GIRK CHANNELS | NORTHEASTERN UNIVERSITY | 2021-08-19 | — | — | US | claimed |
| CN-113260609-A | Aromatic receptor antagonists and methods of use thereof | 美真达治疗公司 | 2021-08-13 | — | — | CN | claimed |
| US-20040116439-A1 | Serine protease inhibitors | TULARIK LIMITED (GB) | 2004-06-17 | — | — | US | claimed |
| EP-1420784-A1 | COMPOUNDS EFFECTING GLUCOKINASE | Astrazeneca AB (SE) | 2004-05-26 | — | — | EP | claimed |
| US-20030216403-A1 | Serine protease inhibitors | TULARIK LIMITED (GB) | 2003-11-20 | — | — | US | claimed |
| US-20030203909-A1 | Fused bicyclic amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2003-10-30 | — | — | US | claimed |
| EP-1310488-A1 | FUSED BICYCLIC AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2003-05-14 | — | — | EP | claimed |
| EP-1294691-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-03-26 | — | — | EP | claimed |
| WO-2003015774-A1 | COMPOUNDS EFFECTING GLUCOKINASE | ASTRAZENECA AB (SE) | 2003-02-27 | — | — | WO | claimed |
| WO-2001096305-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| EP-0381422-B1 | Tetrahydrobenzimidazole derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-10-23 | — | — | EP | claimed |
| US-5344927-A | 5-HT3 antagonist | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |