Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395654 | 0.82 | PIM1 (0.56) | CSNK2A1CSNK2A2CSNK2BCSNK2A3ACMSD | |
| SCHEMBL27509465 | 0.74 | CSNK2A1 (0.47) | ALDH1A1CSNK2A1KDM4ECSNK2A2CSNK2B | |
| SCHEMBL29115389 | 0.74 | PIM1 (0.70) | ALDH1A1CSNK2A1KDM4ECSNK2A2CSNK2B | |
| SCHEMBL2976354 | 0.73 | AKR1B1 (0.76) | ALDH1A1CSNK2A1KDM4ECSNK2A2CSNK2B | |
| SCHEMBL4256569 | 0.73 | ALDH1A1 (0.69) | ALDH1A1CSNK2A1KDM4ECSNK2A2CSNK2B | |
| SCHEMBL18144902 | 0.73 | ALDH1A1 (0.69) | ALDH1A1CSNK2A1KDM4ECSNK2A2CSNK2B | |
| SCHEMBL4545204 | 0.73 | DYRK1A (0.56) | ACMSDTDP1MAOBKCNH2 | |
| SCHEMBL379054 | 0.72 | ALDH1A1 (0.67) | ALDH1A1CSNK2A1KDM4ECSNK2A2CSNK2B | |
| SCHEMBL1504213 | 0.72 | ALDH1A1 (1.00) | ALDH1A1CSNK2A1KDM4ECSNK2A2CSNK2B | |
| SCHEMBL2318176 | 0.72 | ALDH1A1 (0.67) | ALDH1A1CSNK2A1KDM4ECSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716191-B2 | Method of preparing an adduct | UNIVERSITE DE STRASBOURG (FR) | 2014-05-06 | — | — | US | disclosed |
| EP-2446033-B1 | METHOD OF PREPARING AN ADDUCT | UNIV STRASBOURG (FR) | 2013-10-23 | — | — | EP | disclosed |
| US-20120115751-A1 | METHOD OF PREPARING AN ADDUCT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-05-10 | — | — | US | disclosed |
| WO-2010150103-A2 | METHOD OF PREPARING AN ADDUCT | UNIVERSITE DE STRASBOURG (FR) | 2010-12-29 | — | — | WO | disclosed |