Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 8/20 | 0.43 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | HCK | P08631 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031348 | 0.77 | ERN1 (0.48) | DYRK1AMAOAMAOBPTPRCKCNH2 | |
| SCHEMBL4548291 | 0.73 | ALDH1A1 (0.56) | MAOBKCNH2TDP1ACMSD | |
| SCHEMBL978584 | 0.72 | DYRK1A (0.64) | DYRK1AMAOAMAOBFTOACHE | |
| SCHEMBL28532367 | 0.72 | KDM4E (0.62) | DYRK1AMAOAMAOBACHEKCNH2 | |
| SCHEMBL2387259 | 0.72 | DYRK1A (0.56) | DYRK1AMAOAMAOBFTOACHE | |
| SCHEMBL3027975 | 0.69 | PTPRC (0.49) | PTPRCKCNH2TDP1ACMSDERN1 | |
| SCHEMBL365385 | 0.69 | MAOA (0.58) | DYRK1AMAOAMAOBFTOACHE | |
| SCHEMBL24221407 | 0.68 | MAOA (0.54) | DYRK1AMAOAMAOBFTOACHE | |
| SCHEMBL3662195 | 0.68 | DYRK1A (0.55) | DYRK1AMAOAMAOBFTOACHE | |
| SCHEMBL3681299 | 0.67 | FTO (0.61) | DYRK1AMAOAMAOBFTOACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716191-B2 | Method of preparing an adduct | UNIVERSITE DE STRASBOURG (FR) | 2014-05-06 | — | — | US | disclosed |
| US-20120115751-A1 | METHOD OF PREPARING AN ADDUCT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-05-10 | — | — | US | disclosed |