Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | ESRRB | O95718 | 3/20 | 0.34 |
| ▸ | ESRRA | P11474 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320833 | 0.89 | TYR (0.57) | TYRNR1H4RARARARGMIF | |
| SCHEMBL29573454 | 0.89 | TYR (0.57) | TYRNR1H4RARARARGMIF | |
| SCHEMBL676933 | 0.82 | TYR (0.45) | TYRNR1H4RARARARGMIF | |
| SCHEMBL7052327 | 0.79 | TYR (0.48) | TYRNR1H4MIFMAOBMAOA | |
| SCHEMBL4549085 | 0.78 | TYR (0.39) | TYRRARARARGMAOBRARB | |
| SCHEMBL571483 | 0.78 | TYR (0.54) | TYRNR1H4MIFMAOBCYP3A4 | |
| Idronoxil SCHEMBL29353213 | 0.74 | ESR2 (0.49) | TYRNR1H4RARARARGMIF | |
| Idronoxil SCHEMBL149612 | 0.74 | ESR2 (0.49) | TYRNR1H4RARARARGMIF | |
| SCHEMBL13704162 | 0.74 | TYR (0.38) | TYRNR1H4MAOATRPA1CYP3A4 | |
| SCHEMBL30628176 | 0.73 | TYR (0.47) | TYRNR1H4RARARARGMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115942-A1 | Methods for Synthesizing Glycinols, Glyceollins I and II and Isoflavenes and Chromanes Using A Wittig Reaction, and Compositions Made Therewith | THE UNIVERSITY OF TOLEDO | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115942-A1 | Methods for Synthesizing Glycinols, Glyceollins I and II and Isoflavenes and Chromanes Using A Wittig Reaction, and Compositions Made Therewith | UGGT1, GCG, UGT8 | TYR 283/4885NR1H4 1624/4885RARA 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.