SCHEMBL571483

SCHEMBL571483

COc1c(O)ccc(C2=Cc3ccc(O)cc3OC2)c1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.54
NR1H4 Q96RI1 1/20 0.48
MAOB P27338 3/20 0.41
AR P10275 1/20 0.38
PTGS2 P35354 3/20 0.37
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
RECQL P46063 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
MIF P14174 1/20 0.36
ALOX5 P09917 1/20 0.36
PTPN1 P18031 2/20 0.36
APP P05067 1/20 0.35
CXCL12 P48061 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30628176 0.85 TYR (0.47) TYRNR1H4MAOBPTGS2MAPT
SCHEMBL27013667 0.82 PTPN1 (0.49) TYRGAAPTPN1
SCHEMBL29702142 0.82 PTPN1 (0.49) TYRGAAPTPN1
SCHEMBL29573454 0.81 TYR (0.57) TYRNR1H4MAOBMAPTRAB9A
SCHEMBL4320833 0.81 TYR (0.57) TYRNR1H4MAOBMAPTRAB9A
SCHEMBL4549102 0.78 TYR (0.55) TYRNR1H4MAOBKDM4EMIF
SCHEMBL612956 0.76 MAOB (0.49) TYRNR1H4MAOBPTGS2MAPT
SCHEMBL6498965 0.75 NR1H4 (0.45) TYRNR1H4MAOBMAPTKDM4E
SCHEMBL952469 0.74 NR1H4 (0.54) TYRNR1H4MAOBPTGS2MAPT
SCHEMBL13704162 0.73 TYR (0.38) TYRNR1H4ARMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190142940-A1 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2019-05-16 US claimed
US-20120207809-A1 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2012-08-16 US claimed
US-20120076848-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2012-03-29 US claimed
US-20110280909-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-11-17 US claimed
WO-2011011065-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-01-27 WO claimed
WO-2010087983-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2010-08-05 WO claimed
JP-11322530-A None JP disclosed
CN-120154539-A Camellia polypeptide composition with anti-wrinkle, repairing and brightening effects and preparation method and application thereof 上海林清轩生物科技股份有限公司 2025-06-17 CN disclosed
CN-115337235-B Multiple whitening pathway composition containing safflower camellia extract 上海林清轩生物科技有限公司 2023-06-13 CN disclosed
CN-115337235-A Multi-whitening-path composition containing camellia chrysantha extract 上海林清轩生物科技有限公司 2022-11-15 CN disclosed
US-20190142940-A1 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2019-05-16 US disclosed
US-20170334842-A1 INHIBITORS OF THE MITF MOLECULAR PATHWAY UNIVERSITY OF KANSAS 2017-11-23 US disclosed
US-9744237-B2 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2017-08-29 US disclosed
US-20110301105-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2011-12-08 US disclosed
US-20110280909-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-11-17 US disclosed
US-20110129136-A1 Method And System For Screening Of A To-Be-Analyzed Candidate As A Skin-Whitening Agent NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2011-06-02 US disclosed
WO-2011011065-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-01-27 WO disclosed
WO-2010087983-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2010-08-05 WO disclosed
WO-2010039679-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2010-04-08 WO disclosed
JP-H11322530-A SKIN-BEAUTIFYING PREPARATION FOR EXTERNAL USE FOR SKIN POLA CHEM IND INC 1999-11-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334842-A1 INHIBITORS OF THE MITF MOLECULAR PATHWAY MITF, TFEB, TYR TYR 3/4885NR1H4 3243/4885MAOB 666/4885
US-20110301105-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS MKI67, KRT18, PROX1 TYR 141/4885NR1H4 1800/4885MAOB 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.