Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320833 | 0.89 | TYR (0.57) | TYRALOX5MAPTRAB9AALDH1A1 | |
| SCHEMBL29573454 | 0.89 | TYR (0.57) | TYRALOX5MAPTRAB9AALDH1A1 | |
| SCHEMBL6235941 | 0.85 | NISCH (0.48) | TYRNISCHALOX5MAPTRAB9A | |
| SCHEMBL4549102 | 0.79 | TYR (0.55) | TYRALDH1A1MIFESR1ESR2 | |
| SCHEMBL26549421 | 0.79 | NISCH (0.48) | NISCHALOX5MAPTRAB9AALDH1A1 | |
| SCHEMBL21436803 | 0.76 | NISCH (0.48) | NISCHALOX5MAPTRAB9AALDH1A1 | |
| SCHEMBL616344 | 0.74 | RARA (0.46) | TYRNISCHALOX5MAPTRAB9A | |
| SCHEMBL571483 | 0.72 | TYR (0.54) | TYRALOX5MAPTRAB9AMIF | |
| SCHEMBL22625517 | 0.71 | TYR (0.42) | TYRNISCHMAPTRAB9AALDH1A1 | |
| SCHEMBL230113 | 0.71 | NISCH (0.53) | NISCHALOX5MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028762-A1 | NOVEL ANTIMICROBIAL RESISTANCE BLOCKING COMPOSITIONS | ETHICON, INC. (US) | 2003-04-10 | — | — | WO | disclosed |