Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454863 | 0.79 | WNT3A (0.39) | TNKS2SMN1; SMN2DHODH | |
| SCHEMBL19366154 | 0.65 | PIN1 (0.49) | HCAR2GRK6SLC9A1PIN1SMPD3 | |
| SCHEMBL12487639 | 0.65 | SMN1; SMN2 (0.47) | TNKSPARP1TNKS2SMN1; SMN2MAPT | |
| SCHEMBL377866 | 0.60 | BRD4 (0.45) | TNKSPARP1TNKS2 | |
| SCHEMBL13736743 | 0.60 | CYP1A2 (0.49) | GRIN1GRIN2BSMN1; SMN2 | |
| SCHEMBL15570393 | 0.60 | HCAR2 (0.40) | HCAR2MAPTPOLB | |
| SCHEMBL13733863 | 0.59 | CYP1A2 (0.43) | GRIN1GRIN2BSMN1; SMN2 | |
| SCHEMBL25347352 | 0.58 | HTT (0.38) | HCAR2DHODH | |
| SCHEMBL9895127 | 0.58 | CYP1A2 (0.47) | GRIN1GRIN2BSMN1; SMN2 | |
| SCHEMBL21964587 | 0.57 | HCAR2 (0.38) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475654-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2012-07-18 | — | — | EP | disclosed |
| WO-2012033548-A2 | HERBICIDAL BIS-NITROGEN-CONTAINING OXO AND SULFONO HETEROCYCLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011031658-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-17 | — | — | WO | disclosed |