SCHEMBL4549430

SCHEMBL4549430

c1ccc(-c2ccccc2-c2ccc3cc(-c4ccc(-c5cccc6c5oc5ccccc56)cc4)c4ccccc4c3c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.57
GGPS1 O95749 1/20 0.46
PRKDC P78527 7/20 0.42
PTGES2 Q9H7Z7 1/20 0.42
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 3/20 0.37
RAB9A P51151 2/20 0.37
MAOB P27338 1/20 0.37
PLA2G2A P14555 2/20 0.36
PLA2G4A P47712 2/20 0.36
PLA2G10 O15496 1/20 0.36
CDC14B O60729 1/20 0.36
CDC14A Q9UNH5 1/20 0.36
PIK3CD O00329 3/20 0.36
PIK3CB P42338 3/20 0.36
PIK3CA P42336 2/20 0.36
PIK3CG P48736 2/20 0.36
PDE2A O00408 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549423 0.95 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL4549428 0.95 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL4549429 0.93 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL21304235 0.91 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL4549426 0.91 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL22889455 0.89 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL18607535 0.88 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL4549427 0.88 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL21304229 0.88 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL4549366 0.87 ALOX5 (0.60) ALOX5GGPS1PRKDCPTGES2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885GGPS1 1183/4885PRKDC 4132/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885GGPS1 1183/4885PRKDC 4132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.