SCHEMBL4549498

SCHEMBL4549498

CO[C@@H]1[C@@H](OC)[C@H](C)O[C@@H](OC(=O)Nc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)[C@@H]1OC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
TRPV1 Q8NER1 1/20 0.35
ACHE P22303 1/20 0.35
EPHX2 P34913 3/20 0.35
LMNA P02545 1/20 0.35
CHRNA7 P36544 1/20 0.35
SCN10A Q9Y5Y9 1/20 0.35
ABL1 P00519 3/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20550978 1.00 MAPT (0.37) MAPTTRPV1ACHEEPHX2LMNA
SCHEMBL11942657 0.94 MAPT (0.37) MAPTTRPV1ACHEEPHX2LMNA
SCHEMBL16079290 0.94 MAPT (0.36) MAPTTRPV1ACHELMNAABL1
SCHEMBL18098901 0.94 MAPT (0.36) MAPTTRPV1ACHELMNAABL1
SCHEMBL18098874 0.94 ABCG2 (0.34) MAPTABL1ABCG2
SCHEMBL29658131 0.94 ABCG2 (0.34) MAPTABL1ABCG2
SCHEMBL18099074 0.94 ABCG2 (0.34) MAPTABL1ABCG2
SCHEMBL20551001 0.93 MAPT (0.34) MAPTTRPV1ACHELMNACHRNA7
SCHEMBL18098989 0.93 MAPT (0.34) MAPTTRPV1ACHELMNACHRNA7
SCHEMBL18098913 0.91 MAPT (0.33) MAPTTRPV1ACHEEPHX2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 US claimed
WO-2025223904-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-30 WO claimed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 EP claimed
EP-4618760-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-09-24 EP claimed
EP-4618761-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-09-24 EP claimed
WO-2024104814-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 WO claimed
EP-4739691-A1 SUBSTITUTED PYRIDYL/PYRAZINYL DIHYDROPYRROLOTRIAZINE COMPOUNDS FOR COMBATTING PHYTOPATH-OGENIC FUNGI BASF SE (DE) 2026-05-13 EP disclosed
EP-4739690-A1 SUBSTITUTED QUINOLYL/QUINOXALYL DIHYDROPYRROLOTRIAZINE COMPOUNDS FOR COMBATTING PHYTO-PATHOGENIC FUNGI BASF SE (DE) 2026-05-13 EP disclosed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP disclosed
EP-4706394-A2 USE OF ALKOXYPYRAZOLES AS NITRIFICATION INHIBITORS BASF SE (DE) 2026-03-11 EP disclosed
EP-4702006-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS XVI BASF SE (DE) 2026-03-04 EP disclosed
US-12564191-B2 Pesticidal compounds BASF SE (DE) 2026-03-03 US disclosed
WO-2019145140-A1 SILYLETHYNYL HETARYL COMPOUNDS AS NITRIFICATION INHIBITORS BASF SE (DE) 2019-08-01 WO disclosed
WO-2018197466-A1 SUBSTITUTED SUCCINIMIDE DERIVATIVES AS PESTICIDES BASF SE (DE) 2018-11-01 WO disclosed
WO-2018184970-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2018-10-11 WO disclosed
WO-2018153730-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2018-08-30 WO disclosed
EP-2247603-B1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2016-09-28 EP disclosed
US-8178658-B2 Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group DOW AGROSCIENCES, LLC (US) 2012-05-15 US disclosed
US-20090209476-A1 Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group DOW AGROSCIENCES LLC (US) 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209476-A1 Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group DDT, ACHE, NANP MAPT 2297/4885TRPV1 1062/4885ACHE 2/4885
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, ERG28 MAPT 1725/4885TRPV1 3778/4885ACHE 1893/4885
US-12564191-B2 Pesticidal compounds CBR1, CBR3, SCN1B MAPT 3893/4885TRPV1 1984/4885ACHE 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.