Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.81 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.81 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.81 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.81 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.81 |
| ▸ | DRD2 | P14416 | 1/20 | 0.81 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.81 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.81 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.81 |
| ▸ | MAOA | P21397 | 1/20 | 0.81 |
| ▸ | DRD4 | P21917 | 1/20 | 0.81 |
| ▸ | MAOB | P27338 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | HRH1 | P35367 | 1/20 | 0.81 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.81 |
| ▸ | DRD3 | P35462 | 1/20 | 0.81 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.81 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18623769 | 0.92 | OPRM1 (0.76) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| SCHEMBL4545375 | 0.92 | OPRM1 (0.81) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| Fentanyl SCHEMBL8804 | 0.90 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| Fentanyl SCHEMBL916599 | 0.90 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| SCHEMBL1172827 | 0.90 | OPRM1 (0.65) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| SCHEMBL15920013 | 0.89 | OPRM1 (0.80) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| Fentanyl SCHEMBL4971300 | 0.89 | OPRM1 (0.98) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| Fentanyl SCHEMBL4324385 | 0.89 | OPRM1 (0.98) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| Fentanyl SCHEMBL22637301 | 0.89 | OPRM1 (0.98) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| Fentanyl SCHEMBL18249370 | 0.89 | OPRM1 (0.98) | OPRM1OPRD1OPRK1SLC22A1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119291192-A | Kit for detecting content of fentanyl and analogues thereof and application of kit | 中国药科大学 | 2025-01-10 | — | — | CN | claimed |
| CN-122036595-A | Fentanyl hapten, complete antigen thereof and application thereof | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-122036595-A | Fentanyl hapten, complete antigen thereof and application thereof | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20190046523-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | NEKTAR THERAPEUTICS | 2019-02-14 | — | — | US | disclosed |
| US-9827239-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2017-11-28 | — | — | US | disclosed |
| US-20170112826-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | NEKTAR THERAPEUTICS | 2017-04-27 | — | — | US | disclosed |
| US-20170079975-A1 | Compositions, Dosage Forms, and Co-Administration of an Opioid Agonist Compound and an Analgesic Compound | NEKTAR THERAPEUTICS | 2017-03-23 | — | — | US | disclosed |
| US-9512135-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2016-12-06 | — | — | US | disclosed |
| US-9458166-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2016-10-04 | — | — | US | disclosed |
| US-9457024-B2 | Compositions, dosage forms, and co-administration of an opioid agonist compound and a non-steroidal anti-inflammatory drug | NEKTAR THERAPEUTICS | 2016-10-04 | — | — | US | disclosed |
| US-8946285-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140336214-A1 | Compositions, Dosage Forms, and Co-Administration of an Opioid Agonist Compound and an Analgesic Compound | NEKTAR THERAPEUTICS | 2014-11-13 | — | — | US | disclosed |
| US-20140187790-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | NEKTAR THERAPEUTICS (US) | 2014-07-03 | — | — | US | disclosed |
| US-8575196-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2013-11-05 | — | — | US | disclosed |
| US-8569343-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2013-10-29 | — | — | US | disclosed |
| US-8440687-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2013-05-14 | — | — | US | disclosed |
| US-20120264775-A1 | Oligomer-Opioid Agonist Conjugates | NEKTAR THERAPEUTICS (US) | 2012-10-18 | — | — | US | disclosed |
| US-20120184581-A1 | Oligomer-Opioid Agonist Conjugates | NEKTAR THERAPEUTICS (US) | 2012-07-19 | — | — | US | disclosed |
| US-8173666-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2012-05-08 | — | — | US | disclosed |
| US-20100048602-A1 | Oligomer-Opioid Agonist Conjugates | NEKTAR THERAPEUTICS (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112826-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 5/4885OPRK1 3/4885 |
| US-20170079975-A1 | Compositions, Dosage Forms, and Co-Administration of an Opioid Agonist Compound and an Analgesic Compound | OPRL1, OPRM1, OPRK1 | OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885 |
| US-20190046523-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 5/4885OPRK1 3/4885 |
| US-20140336214-A1 | Compositions, Dosage Forms, and Co-Administration of an Opioid Agonist Compound and an Analgesic Compound | OPRL1, OPRM1, OPRK1 | OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885 |
| US-20140187790-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 5/4885OPRK1 3/4885 |
| US-20120184581-A1 | Oligomer-Opioid Agonist Conjugates | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 5/4885OPRK1 3/4885 |
| US-20100048602-A1 | Oligomer-Opioid Agonist Conjugates | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 5/4885OPRK1 3/4885 |
| US-20120264775-A1 | Oligomer-Opioid Agonist Conjugates | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 5/4885OPRK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.