SCHEMBL18623769

SCHEMBL18623769

CCCC(=O)N(c1ccc(OC)cc1)C1CCN(CCc2ccccc2)CC1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 11/20 0.76
OPRD1 P41143 9/20 0.69
OPRK1 P41145 4/20 0.69
SLC22A1 O15245 1/20 0.68
NR1I2 O75469 1/20 0.68
ABCB1 P08183 1/20 0.68
CHRM1 P11229 1/20 0.68
DRD2 P14416 1/20 0.68
ADRA2B P18089 1/20 0.68
ADRA2C P18825 1/20 0.68
CHRM3 P20309 1/20 0.68
MAOA P21397 1/20 0.68
DRD4 P21917 1/20 0.68
MAOB P27338 1/20 0.68
ADRA1A P35348 1/20 0.68
HRH1 P35367 1/20 0.68
ADRA1B P35368 1/20 0.68
DRD3 P35462 1/20 0.68
CHRNA4 P43681 1/20 0.68
SLC6A3 Q01959 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549608 0.92 OPRM1 (0.81) OPRM1OPRD1OPRK1SLC22A1NR1I2
SCHEMBL18623773 0.90 OPRM1 (0.87) OPRM1OPRD1OPRK1SLC22A1NR1I2
SCHEMBL28781766 0.90 CHRM2 (0.74) OPRM1OPRD1OPRK1CHRM3SIGMAR1
SCHEMBL18623766 0.88 OPRM1 (0.75) OPRM1OPRD1OPRK1SLC22A1NR1I2
SCHEMBL28781781 0.85 OPRM1 (0.85) OPRM1
SCHEMBL18623779 0.84 OPRM1 (1.00) OPRM1OPRD1OPRK1SLC22A1NR1I2
SCHEMBL4545375 0.83 OPRM1 (0.81) OPRM1OPRD1OPRK1SLC22A1NR1I2
SCHEMBL24726675 0.82 OPRD1 (1.00) OPRM1OPRD1OPRK1SLC22A1NR1I2
SCHEMBL1686075 0.82 OPRM1 (0.92) OPRM1OPRD1OPRK1SLC22A1NR1I2
SCHEMBL1172827 0.82 OPRM1 (0.65) OPRM1OPRD1OPRK1SLC22A1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12529695-B2 Fentanyl analogue detection methods and kits thereof VERITEQUE USA, INC. (US) 2026-01-20 US disclosed
CN-118556058-A New method 细胞内治疗公司 2024-08-27 CN disclosed
US-20220390439-A1 FENTANYL ANALOGUE DETECTION METHODS AND KITS THEREOF VERITEQUE USA, INC. 2022-12-08 US disclosed
US-20220390439-A1 FENTANYL ANALOGUE DETECTION METHODS AND KITS THEREOF VERITEQUE USA, INC. 2022-12-08 US disclosed
US-20210093557-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE ADAPT PHARMA LTD (IE) 2021-04-01 US disclosed
US-20200030229-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE Adapt Pharma Limited 2020-01-30 US disclosed
US-20190015323-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE Adaph Pharma Limited 2019-01-17 US disclosed
US-20170071851-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE INDIVIOR UK LIMITED (GB) 2017-03-16 US disclosed
US-20170071851-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE INDIVIOR UK LIMITED (GB) 2017-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170071851-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE OPRL1, OPRM1, OPRK1 OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885
US-20210093557-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE OPRL1, OPRM1, OPRK1 OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885
US-12529695-B2 Fentanyl analogue detection methods and kits thereof CA13, CA2, CA12 OPRM1 24/4885OPRD1 6/4885OPRK1 19/4885
US-20190015323-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE OPRL1, OPRM1, OPRK1 OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885
US-20200030229-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE OPRL1, OPRM1, OPRK1 OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.